node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cagg_1261 | Cagg_1264 | Cagg_1261 | Cagg_1264 | PFAM: cobalbumin biosynthesis protein; KEGG: cau:Caur_2562 adenosylcobinamide-phosphate guanylyltransferase. | TIGRFAM: precorrin-3B C17-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: cau:Caur_2565 precorrin-3B C17-methyltransferase. | 0.917 |
Cagg_1261 | Cagg_1267 | Cagg_1261 | Cagg_1267 | PFAM: cobalbumin biosynthesis protein; KEGG: cau:Caur_2562 adenosylcobinamide-phosphate guanylyltransferase. | KEGG: cau:Caur_2568 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. | 0.808 |
Cagg_1261 | Cagg_1269 | Cagg_1261 | Cagg_1269 | PFAM: cobalbumin biosynthesis protein; KEGG: cau:Caur_2562 adenosylcobinamide-phosphate guanylyltransferase. | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: cau:Caur_2570 precorrin-8X methylmutase CbiC/CobH. | 0.800 |
Cagg_1261 | Cagg_1279 | Cagg_1261 | Cagg_1279 | PFAM: cobalbumin biosynthesis protein; KEGG: cau:Caur_2562 adenosylcobinamide-phosphate guanylyltransferase. | KEGG: cau:Caur_2580 cob(I)alamin adenosyltransferase; TIGRFAM: cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. | 0.981 |
Cagg_1261 | Cagg_2177 | Cagg_1261 | Cagg_2177 | PFAM: cobalbumin biosynthesis protein; KEGG: cau:Caur_2562 adenosylcobinamide-phosphate guanylyltransferase. | PFAM: Phosphoglycerate mutase; KEGG: cau:Caur_1199 phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. | 0.500 |
Cagg_1261 | cbiA | Cagg_1261 | Cagg_1262 | PFAM: cobalbumin biosynthesis protein; KEGG: cau:Caur_2562 adenosylcobinamide-phosphate guanylyltransferase. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.969 |
Cagg_1261 | cobD | Cagg_1261 | Cagg_1272 | PFAM: cobalbumin biosynthesis protein; KEGG: cau:Caur_2562 adenosylcobinamide-phosphate guanylyltransferase. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.993 |
Cagg_1261 | cobQ | Cagg_1261 | Cagg_1259 | PFAM: cobalbumin biosynthesis protein; KEGG: cau:Caur_2562 adenosylcobinamide-phosphate guanylyltransferase. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.997 |
Cagg_1261 | cobS | Cagg_1261 | Cagg_2176 | PFAM: cobalbumin biosynthesis protein; KEGG: cau:Caur_2562 adenosylcobinamide-phosphate guanylyltransferase. | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.988 |
Cagg_1261 | cobT | Cagg_1261 | Cagg_1277 | PFAM: cobalbumin biosynthesis protein; KEGG: cau:Caur_2562 adenosylcobinamide-phosphate guanylyltransferase. | Nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.991 |
Cagg_1264 | Cagg_1261 | Cagg_1264 | Cagg_1261 | TIGRFAM: precorrin-3B C17-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: cau:Caur_2565 precorrin-3B C17-methyltransferase. | PFAM: cobalbumin biosynthesis protein; KEGG: cau:Caur_2562 adenosylcobinamide-phosphate guanylyltransferase. | 0.917 |
Cagg_1264 | Cagg_1267 | Cagg_1264 | Cagg_1267 | TIGRFAM: precorrin-3B C17-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: cau:Caur_2565 precorrin-3B C17-methyltransferase. | KEGG: cau:Caur_2568 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. | 0.999 |
Cagg_1264 | Cagg_1269 | Cagg_1264 | Cagg_1269 | TIGRFAM: precorrin-3B C17-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: cau:Caur_2565 precorrin-3B C17-methyltransferase. | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: cau:Caur_2570 precorrin-8X methylmutase CbiC/CobH. | 0.999 |
Cagg_1264 | Cagg_1279 | Cagg_1264 | Cagg_1279 | TIGRFAM: precorrin-3B C17-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: cau:Caur_2565 precorrin-3B C17-methyltransferase. | KEGG: cau:Caur_2580 cob(I)alamin adenosyltransferase; TIGRFAM: cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. | 0.829 |
Cagg_1264 | Cagg_2177 | Cagg_1264 | Cagg_2177 | TIGRFAM: precorrin-3B C17-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: cau:Caur_2565 precorrin-3B C17-methyltransferase. | PFAM: Phosphoglycerate mutase; KEGG: cau:Caur_1199 phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. | 0.687 |
Cagg_1264 | cbiA | Cagg_1264 | Cagg_1262 | TIGRFAM: precorrin-3B C17-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: cau:Caur_2565 precorrin-3B C17-methyltransferase. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.988 |
Cagg_1264 | cobD | Cagg_1264 | Cagg_1272 | TIGRFAM: precorrin-3B C17-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: cau:Caur_2565 precorrin-3B C17-methyltransferase. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.949 |
Cagg_1264 | cobQ | Cagg_1264 | Cagg_1259 | TIGRFAM: precorrin-3B C17-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: cau:Caur_2565 precorrin-3B C17-methyltransferase. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.997 |
Cagg_1264 | cobS | Cagg_1264 | Cagg_2176 | TIGRFAM: precorrin-3B C17-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: cau:Caur_2565 precorrin-3B C17-methyltransferase. | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.990 |
Cagg_1264 | cobT | Cagg_1264 | Cagg_1277 | TIGRFAM: precorrin-3B C17-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: cau:Caur_2565 precorrin-3B C17-methyltransferase. | Nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.950 |