node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cagg_0318 | ffh | Cagg_0318 | Cagg_2671 | TIGRFAM: hemolysin A; PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; RNA-binding S4 domain protein; KEGG: cau:Caur_3678 hemolysin A. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.455 |
Cagg_0318 | nadK | Cagg_0318 | Cagg_1593 | TIGRFAM: hemolysin A; PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; RNA-binding S4 domain protein; KEGG: cau:Caur_3678 hemolysin A. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.659 |
Cagg_0600 | Cagg_3394 | Cagg_0600 | Cagg_3394 | PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: cau:Caur_2828 TPR repeat-containing protein. | PFAM: AMP-dependent synthetase and ligase; Enoyl-CoA hydratase/isomerase; Alcohol dehydrogenase GroES domain protein; KEGG: cau:Caur_0613 AMP-dependent synthetase and ligase. | 0.577 |
Cagg_0600 | nadE | Cagg_0600 | Cagg_2533 | PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: cau:Caur_2828 TPR repeat-containing protein. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.492 |
Cagg_0600 | nadK | Cagg_0600 | Cagg_1593 | PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: cau:Caur_2828 TPR repeat-containing protein. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.454 |
Cagg_1592 | nadK | Cagg_1592 | Cagg_1593 | PFAM: AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: cau:Caur_1865 ATPase. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.591 |
Cagg_1594 | nadK | Cagg_1594 | Cagg_1593 | PFAM: N-6 Adenine-specific DNA methylase; KEGG: cau:Caur_1067 hypothetical protein. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.517 |
Cagg_2636 | Cagg_3394 | Cagg_2636 | Cagg_3394 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cau:Caur_2080 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. | PFAM: AMP-dependent synthetase and ligase; Enoyl-CoA hydratase/isomerase; Alcohol dehydrogenase GroES domain protein; KEGG: cau:Caur_0613 AMP-dependent synthetase and ligase. | 0.855 |
Cagg_2636 | ffh | Cagg_2636 | Cagg_2671 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cau:Caur_2080 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.535 |
Cagg_2636 | nadE | Cagg_2636 | Cagg_2533 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cau:Caur_2080 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.470 |
Cagg_2636 | nadK | Cagg_2636 | Cagg_1593 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cau:Caur_2080 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.493 |
Cagg_3394 | Cagg_0600 | Cagg_3394 | Cagg_0600 | PFAM: AMP-dependent synthetase and ligase; Enoyl-CoA hydratase/isomerase; Alcohol dehydrogenase GroES domain protein; KEGG: cau:Caur_0613 AMP-dependent synthetase and ligase. | PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: cau:Caur_2828 TPR repeat-containing protein. | 0.577 |
Cagg_3394 | Cagg_2636 | Cagg_3394 | Cagg_2636 | PFAM: AMP-dependent synthetase and ligase; Enoyl-CoA hydratase/isomerase; Alcohol dehydrogenase GroES domain protein; KEGG: cau:Caur_0613 AMP-dependent synthetase and ligase. | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cau:Caur_2080 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. | 0.855 |
Cagg_3394 | cobB | Cagg_3394 | Cagg_0910 | PFAM: AMP-dependent synthetase and ligase; Enoyl-CoA hydratase/isomerase; Alcohol dehydrogenase GroES domain protein; KEGG: cau:Caur_0613 AMP-dependent synthetase and ligase. | PFAM: Silent information regulator protein Sir2; KEGG: cau:Caur_2936 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily. | 0.822 |
Cagg_3394 | nadE | Cagg_3394 | Cagg_2533 | PFAM: AMP-dependent synthetase and ligase; Enoyl-CoA hydratase/isomerase; Alcohol dehydrogenase GroES domain protein; KEGG: cau:Caur_0613 AMP-dependent synthetase and ligase. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.661 |
Cagg_3394 | nadK | Cagg_3394 | Cagg_1593 | PFAM: AMP-dependent synthetase and ligase; Enoyl-CoA hydratase/isomerase; Alcohol dehydrogenase GroES domain protein; KEGG: cau:Caur_0613 AMP-dependent synthetase and ligase. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.479 |
cobB | Cagg_3394 | Cagg_0910 | Cagg_3394 | PFAM: Silent information regulator protein Sir2; KEGG: cau:Caur_2936 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily. | PFAM: AMP-dependent synthetase and ligase; Enoyl-CoA hydratase/isomerase; Alcohol dehydrogenase GroES domain protein; KEGG: cau:Caur_0613 AMP-dependent synthetase and ligase. | 0.822 |
cobB | nadD | Cagg_0910 | Cagg_3085 | PFAM: Silent information regulator protein Sir2; KEGG: cau:Caur_2936 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.930 |
cobB | nadE | Cagg_0910 | Cagg_2533 | PFAM: Silent information regulator protein Sir2; KEGG: cau:Caur_2936 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.957 |
cobB | nadK | Cagg_0910 | Cagg_1593 | PFAM: Silent information regulator protein Sir2; KEGG: cau:Caur_2936 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.923 |