STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadKATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (276 aa)    
Predicted Functional Partners:
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.958
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.950
cobB
PFAM: Silent information regulator protein Sir2; KEGG: cau:Caur_2936 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily.
  
 
 0.923
Cagg_0318
TIGRFAM: hemolysin A; PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; RNA-binding S4 domain protein; KEGG: cau:Caur_3678 hemolysin A.
  
  
 0.659
Cagg_1592
PFAM: AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: cau:Caur_1865 ATPase.
  
    0.591
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
 
    0.535
Cagg_1594
PFAM: N-6 Adenine-specific DNA methylase; KEGG: cau:Caur_1067 hypothetical protein.
       0.517
Cagg_2636
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cau:Caur_2080 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
       0.493
Cagg_3394
PFAM: AMP-dependent synthetase and ligase; Enoyl-CoA hydratase/isomerase; Alcohol dehydrogenase GroES domain protein; KEGG: cau:Caur_0613 AMP-dependent synthetase and ligase.
  
 
 0.479
Cagg_0600
PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: cau:Caur_2828 TPR repeat-containing protein.
     
 0.454
Your Current Organism:
Chloroflexus aggregans
NCBI taxonomy Id: 326427
Other names: C. aggregans DSM 9485, Chloroflexus aggregans DSM 9485, Chloroflexus aggregans MD-66, Chloroflexus aggregans str. DSM 9485, Chloroflexus aggregans strain DSM 9485
Server load: low (32%) [HD]