node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PSHAa0126 | PSHAa2167 | PSHAa0126 | PSHAa2167 | Putative hydrolase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.903 |
PSHAa0126 | PSHAa2497 | PSHAa0126 | PSHAa2497 | Putative hydrolase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative enzyme with a phosphatase-like domain, HAD-superfamily hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.916 |
PSHAa0126 | cdd | PSHAa0126 | PSHAb0315 | Putative hydrolase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 0.900 |
PSHAa0126 | deoD | PSHAa0126 | PSHAb0082 | Putative hydrolase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Purine nucleoside phosphorylase (Inosine phosphorylase) (PNP); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.903 |
PSHAa0126 | ppnP | PSHAa0126 | PSHAa0672 | Putative hydrolase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Conserved protein of unknown function; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.918 |
PSHAa0126 | tdk | PSHAa0126 | PSHAb0294 | Putative hydrolase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Thymidine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.902 |
PSHAa0126 | thyA | PSHAa0126 | PSHAa0749 | Putative hydrolase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Thymidylate synthetase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.902 |
PSHAa0126 | tmk | PSHAa0126 | PSHAa1803 | Putative hydrolase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.901 |
PSHAa0126 | udp | PSHAa0126 | PSHAb0316 | Putative hydrolase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | 0.901 |
PSHAa0126 | ushA | PSHAa0126 | PSHAb0345 | Putative hydrolase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Protein ushA; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the 5'-nucleotidase family. | 0.903 |
PSHAa2167 | PSHAa0126 | PSHAa2167 | PSHAa0126 | Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative hydrolase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.903 |
PSHAa2167 | PSHAa2497 | PSHAa2167 | PSHAa2497 | Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative enzyme with a phosphatase-like domain, HAD-superfamily hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.915 |
PSHAa2167 | cdd | PSHAa2167 | PSHAb0315 | Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 0.906 |
PSHAa2167 | deoD | PSHAa2167 | PSHAb0082 | Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Purine nucleoside phosphorylase (Inosine phosphorylase) (PNP); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.901 |
PSHAa2167 | ppnP | PSHAa2167 | PSHAa0672 | Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Conserved protein of unknown function; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.900 |
PSHAa2167 | tdk | PSHAa2167 | PSHAb0294 | Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Thymidine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.921 |
PSHAa2167 | thyA | PSHAa2167 | PSHAa0749 | Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Thymidylate synthetase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.903 |
PSHAa2167 | tmk | PSHAa2167 | PSHAa1803 | Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.914 |
PSHAa2167 | udp | PSHAa2167 | PSHAb0316 | Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | 0.901 |
PSHAa2167 | ushA | PSHAa2167 | PSHAb0345 | Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Protein ushA; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the 5'-nucleotidase family. | 0.949 |