node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PSHAa0110 | clpA | PSHAa0110 | PSHAa1724 | Putative DnaJ-class molecular chaperone; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; molecular chaperone. | ATP-dependent specificity subunit of clpA-clpP serine protease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ClpA/ClpB family. | 0.680 |
PSHAa0110 | clpB | PSHAa0110 | PSHAa0935 | Putative DnaJ-class molecular chaperone; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; molecular chaperone. | ATP-dependent protease, Hsp 100, part of multi-chaperone system with DnaK, DnaJ, and GrpE; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.680 |
PSHAa0110 | dnaK | PSHAa0110 | PSHAb0357 | Putative DnaJ-class molecular chaperone; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; molecular chaperone. | Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa protein) (HSP70); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.846 |
PSHAa0110 | groL | PSHAa0110 | PSHAa0259 | Putative DnaJ-class molecular chaperone; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; molecular chaperone. | 60 kDa chaperonin (Protein Cpn60) (groEL protein); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.722 |
PSHAa0110 | groS | PSHAa0110 | PSHAa0260 | Putative DnaJ-class molecular chaperone; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; molecular chaperone. | 10 kDa chaperonin (Protein Cpn10) (groES protein); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.576 |
PSHAa0110 | grpE | PSHAa0110 | PSHAa1222 | Putative DnaJ-class molecular chaperone; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; molecular chaperone. | Hsp 24 DnaK nucleotide exchange factor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several [...] | 0.797 |
PSHAa0110 | htpG | PSHAa0110 | PSHAa1207 | Putative DnaJ-class molecular chaperone; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; molecular chaperone. | Chaperone protein htpG; Molecular chaperone. Has ATPase activity. | 0.891 |
cbpA | clpA | PSHAa2878 | PSHAa1724 | Curved DNA-binding protein, co-chaperone of DnaK (Hsp40 family); Function of strongly homologous gene; molecular chaperone. | ATP-dependent specificity subunit of clpA-clpP serine protease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ClpA/ClpB family. | 0.720 |
cbpA | clpB | PSHAa2878 | PSHAa0935 | Curved DNA-binding protein, co-chaperone of DnaK (Hsp40 family); Function of strongly homologous gene; molecular chaperone. | ATP-dependent protease, Hsp 100, part of multi-chaperone system with DnaK, DnaJ, and GrpE; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.720 |
cbpA | dnaK | PSHAa2878 | PSHAb0357 | Curved DNA-binding protein, co-chaperone of DnaK (Hsp40 family); Function of strongly homologous gene; molecular chaperone. | Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa protein) (HSP70); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.956 |
cbpA | groL | PSHAa2878 | PSHAa0259 | Curved DNA-binding protein, co-chaperone of DnaK (Hsp40 family); Function of strongly homologous gene; molecular chaperone. | 60 kDa chaperonin (Protein Cpn60) (groEL protein); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.754 |
cbpA | groS | PSHAa2878 | PSHAa0260 | Curved DNA-binding protein, co-chaperone of DnaK (Hsp40 family); Function of strongly homologous gene; molecular chaperone. | 10 kDa chaperonin (Protein Cpn10) (groES protein); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.645 |
cbpA | grpE | PSHAa2878 | PSHAa1222 | Curved DNA-binding protein, co-chaperone of DnaK (Hsp40 family); Function of strongly homologous gene; molecular chaperone. | Hsp 24 DnaK nucleotide exchange factor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several [...] | 0.903 |
cbpA | htpG | PSHAa2878 | PSHAa1207 | Curved DNA-binding protein, co-chaperone of DnaK (Hsp40 family); Function of strongly homologous gene; molecular chaperone. | Chaperone protein htpG; Molecular chaperone. Has ATPase activity. | 0.891 |
clpA | PSHAa0110 | PSHAa1724 | PSHAa0110 | ATP-dependent specificity subunit of clpA-clpP serine protease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ClpA/ClpB family. | Putative DnaJ-class molecular chaperone; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; molecular chaperone. | 0.680 |
clpA | cbpA | PSHAa1724 | PSHAa2878 | ATP-dependent specificity subunit of clpA-clpP serine protease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ClpA/ClpB family. | Curved DNA-binding protein, co-chaperone of DnaK (Hsp40 family); Function of strongly homologous gene; molecular chaperone. | 0.720 |
clpA | dnaJ | PSHAa1724 | PSHAb0358 | ATP-dependent specificity subunit of clpA-clpP serine protease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ClpA/ClpB family. | Chaperone protein dnaJ (Heat shock protein J) (HSP40), co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Sever [...] | 0.735 |
clpA | dnaK | PSHAa1724 | PSHAb0357 | ATP-dependent specificity subunit of clpA-clpP serine protease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ClpA/ClpB family. | Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa protein) (HSP70); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.872 |
clpA | groL | PSHAa1724 | PSHAa0259 | ATP-dependent specificity subunit of clpA-clpP serine protease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ClpA/ClpB family. | 60 kDa chaperonin (Protein Cpn60) (groEL protein); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.626 |
clpA | groS | PSHAa1724 | PSHAa0260 | ATP-dependent specificity subunit of clpA-clpP serine protease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ClpA/ClpB family. | 10 kDa chaperonin (Protein Cpn10) (groES protein); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.674 |