node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AM1_0805 | mraY | AM1_0805 | AM1_5787 | Conserved hypothetical protein. | phospho-N-acetylmuramoyl-pentapeptide- transferase, putative; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.436 |
AM1_0805 | murB | AM1_0805 | AM1_1799 | Conserved hypothetical protein. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.679 |
AM1_0805 | murC | AM1_0805 | AM1_1800 | Conserved hypothetical protein. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.873 |
AM1_0805 | murD | AM1_0805 | AM1_1525 | Conserved hypothetical protein. | UDP-N-acetylmuramoylalanine--D-glutamate ligase, putative; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.874 |
AM1_0805 | murE | AM1_0805 | AM1_1404 | Conserved hypothetical protein. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.607 |
AM1_0805 | murF | AM1_0805 | AM1_2853 | Conserved hypothetical protein. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.782 |
AM1_0805 | murG | AM1_0805 | AM1_4648 | Conserved hypothetical protein. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase, putative; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.916 |
glsA | murD | AM1_0365 | AM1_1525 | Glutaminase; Belongs to the glutaminase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase, putative; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.901 |
glsA | murI | AM1_0365 | AM1_0602 | Glutaminase; Belongs to the glutaminase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.931 |
glsA | purQ | AM1_0365 | AM1_1434 | Glutaminase; Belongs to the glutaminase family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.900 |
mraY | AM1_0805 | AM1_5787 | AM1_0805 | phospho-N-acetylmuramoyl-pentapeptide- transferase, putative; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Conserved hypothetical protein. | 0.436 |
mraY | murB | AM1_5787 | AM1_1799 | phospho-N-acetylmuramoyl-pentapeptide- transferase, putative; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.815 |
mraY | murC | AM1_5787 | AM1_1800 | phospho-N-acetylmuramoyl-pentapeptide- transferase, putative; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.886 |
mraY | murD | AM1_5787 | AM1_1525 | phospho-N-acetylmuramoyl-pentapeptide- transferase, putative; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylmuramoylalanine--D-glutamate ligase, putative; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.961 |
mraY | murE | AM1_5787 | AM1_1404 | phospho-N-acetylmuramoyl-pentapeptide- transferase, putative; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.888 |
mraY | murF | AM1_5787 | AM1_2853 | phospho-N-acetylmuramoyl-pentapeptide- transferase, putative; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.993 |
mraY | murG | AM1_5787 | AM1_4648 | phospho-N-acetylmuramoyl-pentapeptide- transferase, putative; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase, putative; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.986 |
mraY | murI | AM1_5787 | AM1_0602 | phospho-N-acetylmuramoyl-pentapeptide- transferase, putative; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.474 |
murB | AM1_0805 | AM1_1799 | AM1_0805 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | Conserved hypothetical protein. | 0.679 |
murB | mraY | AM1_1799 | AM1_5787 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | phospho-N-acetylmuramoyl-pentapeptide- transferase, putative; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.815 |