node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AM1_2057 | clpC | AM1_2057 | AM1_1947 | DnaK family protein; Belongs to the heat shock protein 70 family. | ATP-dependent protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | 0.674 |
AM1_2057 | clpP | AM1_2057 | AM1_2330 | DnaK family protein; Belongs to the heat shock protein 70 family. | ATP-dependent Clp protease, proteolytic subunit ClpP, putative; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.405 |
AM1_2057 | clpP-2 | AM1_2057 | AM1_2331 | DnaK family protein; Belongs to the heat shock protein 70 family. | ATP-dependent Clp protease, proteolytic subunit ClpP, putative; Belongs to the peptidase S14 family. | 0.405 |
AM1_2057 | clpP-3 | AM1_2057 | AM1_3449 | DnaK family protein; Belongs to the heat shock protein 70 family. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.405 |
AM1_2057 | grpE | AM1_2057 | AM1_0421 | DnaK family protein; Belongs to the heat shock protein 70 family. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.935 |
clpC | AM1_2057 | AM1_1947 | AM1_2057 | ATP-dependent protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | DnaK family protein; Belongs to the heat shock protein 70 family. | 0.674 |
clpC | clpP | AM1_1947 | AM1_2330 | ATP-dependent protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, proteolytic subunit ClpP, putative; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.771 |
clpC | clpP-2 | AM1_1947 | AM1_2331 | ATP-dependent protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, proteolytic subunit ClpP, putative; Belongs to the peptidase S14 family. | 0.795 |
clpC | clpP-3 | AM1_1947 | AM1_3449 | ATP-dependent protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.791 |
clpC | clpS | AM1_1947 | AM1_3896 | ATP-dependent protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.614 |
clpC | dnaK | AM1_1947 | AM1_0422 | ATP-dependent protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.709 |
clpC | dnaK-2 | AM1_1947 | AM1_2440 | ATP-dependent protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.688 |
clpC | dnaK-3 | AM1_1947 | AM1_5692 | ATP-dependent protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.711 |
clpC | grpE | AM1_1947 | AM1_0421 | ATP-dependent protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.746 |
clpC | sdhA | AM1_1947 | AM1_2784 | ATP-dependent protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | 0.620 |
clpP | AM1_2057 | AM1_2330 | AM1_2057 | ATP-dependent Clp protease, proteolytic subunit ClpP, putative; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | DnaK family protein; Belongs to the heat shock protein 70 family. | 0.405 |
clpP | clpC | AM1_2330 | AM1_1947 | ATP-dependent Clp protease, proteolytic subunit ClpP, putative; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | 0.771 |
clpP | clpP-2 | AM1_2330 | AM1_2331 | ATP-dependent Clp protease, proteolytic subunit ClpP, putative; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent Clp protease, proteolytic subunit ClpP, putative; Belongs to the peptidase S14 family. | 0.717 |
clpP | clpS | AM1_2330 | AM1_3896 | ATP-dependent Clp protease, proteolytic subunit ClpP, putative; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.461 |
clpP | dnaK | AM1_2330 | AM1_0422 | ATP-dependent Clp protease, proteolytic subunit ClpP, putative; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.461 |