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mutM protein (Acaryochloris marina) - STRING interaction network
"mutM" - Formamidopyrimidine-DNA glycosylase in Acaryochloris marina
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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mutMFormamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3’- and 5’-phosphates (284 aa)    
Predicted Functional Partners:
coaE
Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3’-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family (200 aa)
 
   
  0.900
mutY
annotation not available (368 aa)
   
 
  0.833
ruvB
Holliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (375 aa)
   
   
  0.821
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (957 aa)
   
   
  0.817
psaE
Photosystem I reaction center subunit IV; Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase (89 aa)
         
  0.811
recG
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3’- to 5’- polarity. Unwinds branched duplex DNA (Y-DNA) (818 aa)
   
   
  0.809
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (200 aa)
         
  0.807
AM1_2891
annotation not available (795 aa)
   
   
  0.805
mutL
annotation not available (573 aa)
   
   
  0.804
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination (293 aa)
     
   
  0.800
Your Current Organism:
Acaryochloris marina
NCBI taxonomy Id: 329726
Other names: A. marina MBIC11017, Acaryochloris marina, Acaryochloris marina MBIC11017
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