node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Saci_0060 | bas1 | Saci_0060 | Saci_0058 | Conserved protein; Homolog is also found in Pyrococcus horikoshii. | Conserved Archaeal 2-cys peroxiredoxin. | 0.587 |
Saci_0060 | ppcA | Saci_0060 | Saci_0059 | Conserved protein; Homolog is also found in Pyrococcus horikoshii. | Conserved Archaeal protein; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family. | 0.790 |
Saci_1417 | Saci_1648 | Saci_1417 | Saci_1648 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.934 |
Saci_1417 | eno | Saci_1417 | Saci_1377 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.947 |
Saci_1417 | pckG | Saci_1417 | Saci_1100 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. | 0.911 |
Saci_1417 | ppcA | Saci_1417 | Saci_0059 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | Conserved Archaeal protein; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family. | 0.922 |
Saci_1648 | Saci_1417 | Saci_1648 | Saci_1417 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 0.934 |
Saci_1648 | cisY | Saci_1648 | Saci_0243 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Citrate synthase. | 0.676 |
Saci_1648 | eno | Saci_1648 | Saci_1377 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.998 |
Saci_1648 | mdh | Saci_1648 | Saci_0246 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Lactate/malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. | 0.848 |
Saci_1648 | pckG | Saci_1648 | Saci_1100 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. | 0.960 |
Saci_1648 | ppcA | Saci_1648 | Saci_0059 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Conserved Archaeal protein; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family. | 0.907 |
bas1 | Saci_0060 | Saci_0058 | Saci_0060 | Conserved Archaeal 2-cys peroxiredoxin. | Conserved protein; Homolog is also found in Pyrococcus horikoshii. | 0.587 |
bas1 | ppcA | Saci_0058 | Saci_0059 | Conserved Archaeal 2-cys peroxiredoxin. | Conserved Archaeal protein; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family. | 0.611 |
cisY | Saci_1648 | Saci_0243 | Saci_1648 | Citrate synthase. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.676 |
cisY | eno | Saci_0243 | Saci_1377 | Citrate synthase. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.824 |
cisY | mas | Saci_0243 | Saci_2190 | Citrate synthase. | Malate synthase. | 0.983 |
cisY | mdh | Saci_0243 | Saci_0246 | Citrate synthase. | Lactate/malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. | 0.999 |
cisY | pckG | Saci_0243 | Saci_1100 | Citrate synthase. | Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. | 0.976 |
cisY | ppcA | Saci_0243 | Saci_0059 | Citrate synthase. | Conserved Archaeal protein; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family. | 0.838 |