node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Saci_2363 | argS | Saci_2363 | Saci_1396 | threonyl-tRNA synthetase; Insert not found in other Archaea. | arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.657 |
Saci_2363 | ftsY | Saci_2363 | Saci_1462 | threonyl-tRNA synthetase; Insert not found in other Archaea. | Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.689 |
Saci_2363 | ileS | Saci_2363 | Saci_0599 | threonyl-tRNA synthetase; Insert not found in other Archaea. | isoleucine-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.908 |
Saci_2363 | pheT | Saci_2363 | Saci_1510 | threonyl-tRNA synthetase; Insert not found in other Archaea. | phenylalanyl-tRNA synthetase beta chain. | 0.700 |
Saci_2363 | serS | Saci_2363 | Saci_1584 | threonyl-tRNA synthetase; Insert not found in other Archaea. | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.842 |
Saci_2363 | srp54 | Saci_2363 | Saci_1310 | threonyl-tRNA synthetase; Insert not found in other Archaea. | Signal recognition 54 kDa protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.747 |
Saci_2363 | thrS-cat | Saci_2363 | Saci_1261 | threonyl-tRNA synthetase; Insert not found in other Archaea. | threonine-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also activates L-serine and transfers it to tRNA(Thr) but cannot deacylate incorrectly charged amino acid; unlike most archaea the editing function is found in a freestanding protein. | 0.853 |
Saci_2363 | trpS | Saci_2363 | Saci_0450 | threonyl-tRNA synthetase; Insert not found in other Archaea. | tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.813 |
Saci_2363 | tys1 | Saci_2363 | Saci_0076 | threonyl-tRNA synthetase; Insert not found in other Archaea. | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily. | 0.852 |
Saci_2363 | valS | Saci_2363 | Saci_1430 | threonyl-tRNA synthetase; Insert not found in other Archaea. | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. | 0.916 |
argS | Saci_2363 | Saci_1396 | Saci_2363 | arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | threonyl-tRNA synthetase; Insert not found in other Archaea. | 0.657 |
argS | ftsY | Saci_1396 | Saci_1462 | arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.574 |
argS | ileS | Saci_1396 | Saci_0599 | arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | isoleucine-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.990 |
argS | pheT | Saci_1396 | Saci_1510 | arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | phenylalanyl-tRNA synthetase beta chain. | 0.887 |
argS | serS | Saci_1396 | Saci_1584 | arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.963 |
argS | srp54 | Saci_1396 | Saci_1310 | arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Signal recognition 54 kDa protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.765 |
argS | thrS-cat | Saci_1396 | Saci_1261 | arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | threonine-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also activates L-serine and transfers it to tRNA(Thr) but cannot deacylate incorrectly charged amino acid; unlike most archaea the editing function is found in a freestanding protein. | 0.719 |
argS | trpS | Saci_1396 | Saci_0450 | arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.801 |
argS | tys1 | Saci_1396 | Saci_0076 | arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily. | 0.888 |
argS | valS | Saci_1396 | Saci_1430 | arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. | 0.925 |