node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Saci_0759 | argC | Saci_0759 | Saci_0750 | Conserved Archaeal protein. | N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. | 0.501 |
Saci_0759 | argD | Saci_0759 | Saci_0755 | Conserved Archaeal protein. | Acetylornithine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. | 0.751 |
Saci_0759 | lysK | Saci_0759 | Saci_0756 | Conserved Archaeal protein. | Peptidase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine. | 0.751 |
Saci_0759 | lysM | Saci_0759 | Saci_0752 | Conserved Archaeal protein. | Lrp-like transcriptional regulator. | 0.501 |
Saci_0759 | lysW | Saci_0759 | Saci_0753 | Conserved Archaeal protein. | Conserved protein; Carrier protein that bears the covalently bound substrates for arginine and lysine biosynthesis; bound L-glutamate is sequentially converted to L-ornithine, while bound alpha-aminoadipate (AAA) is sequentially converted to L-lysine. | 0.683 |
Saci_0759 | lysX | Saci_0759 | Saci_0754 | Conserved Archaeal protein. | Conserved Archaeal protein; Catalyzes the ATP-dependent formation of a covalent bond between the amino group of alpha-aminoadipate (AAA) and the gamma- carboxyl group of the C-terminal glutamate residue in LysW. Belongs to the RimK family. LysX subfamily. | 0.751 |
Saci_0759 | lysZ | Saci_0759 | Saci_0751 | Conserved Archaeal protein. | Amino acid kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily. | 0.501 |
Saci_0759 | rps8e | Saci_0759 | Saci_0758 | Conserved Archaeal protein. | 30S ribosomal protein S8E. | 0.869 |
Saci_0759 | uppS | Saci_0759 | Saci_0757 | Conserved Archaeal protein. | Undecaprenyl pyrophosphate synthetase; Generates tritrans,heptacis-undecaprenyl diphosphate from isopentenyl pyrophosphate (IPP) and geranylgeranyl diphosphate. It is probably the precursor of glycosyl carrier lipids; Belongs to the UPP synthase family. | 0.797 |
argC | Saci_0759 | Saci_0750 | Saci_0759 | N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. | Conserved Archaeal protein. | 0.501 |
argC | argD | Saci_0750 | Saci_0755 | N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. | Acetylornithine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. | 0.999 |
argC | argF | Saci_0750 | Saci_1408 | N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | 0.962 |
argC | lysK | Saci_0750 | Saci_0756 | N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. | Peptidase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine. | 0.878 |
argC | lysM | Saci_0750 | Saci_0752 | N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. | Lrp-like transcriptional regulator. | 0.878 |
argC | lysW | Saci_0750 | Saci_0753 | N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. | Conserved protein; Carrier protein that bears the covalently bound substrates for arginine and lysine biosynthesis; bound L-glutamate is sequentially converted to L-ornithine, while bound alpha-aminoadipate (AAA) is sequentially converted to L-lysine. | 0.852 |
argC | lysX | Saci_0750 | Saci_0754 | N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. | Conserved Archaeal protein; Catalyzes the ATP-dependent formation of a covalent bond between the amino group of alpha-aminoadipate (AAA) and the gamma- carboxyl group of the C-terminal glutamate residue in LysW. Belongs to the RimK family. LysX subfamily. | 0.692 |
argC | lysZ | Saci_0750 | Saci_0751 | N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. | Amino acid kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily. | 0.999 |
argC | rps8e | Saci_0750 | Saci_0758 | N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. | 30S ribosomal protein S8E. | 0.501 |
argC | uppS | Saci_0750 | Saci_0757 | N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. | Undecaprenyl pyrophosphate synthetase; Generates tritrans,heptacis-undecaprenyl diphosphate from isopentenyl pyrophosphate (IPP) and geranylgeranyl diphosphate. It is probably the precursor of glycosyl carrier lipids; Belongs to the UPP synthase family. | 0.665 |
argD | Saci_0759 | Saci_0755 | Saci_0759 | Acetylornithine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. | Conserved Archaeal protein. | 0.751 |