STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uppSUndecaprenyl pyrophosphate synthetase; Generates tritrans,heptacis-undecaprenyl diphosphate from isopentenyl pyrophosphate (IPP) and geranylgeranyl diphosphate. It is probably the precursor of glycosyl carrier lipids; Belongs to the UPP synthase family. (262 aa)    
Predicted Functional Partners:
Saci_0995
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
 
 0.987
gds
Geranylgeranyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl pyrophosphate with the allylic pyrophosphates to yield geranylgeranyl diphosphate (GGPP) which is a precursor of the ether-linked lipids. It is able to use dimethylallyl diphosphate (DMAPP), geranyl diphosphate (GPP), and (all- E)-geranyl diphosphate (E-FPP) as an allylic substrate.
 
 
 0.968
Saci_0068
Conserved protein.
 
  
 0.910
pyrH
Amino acid kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.890
Saci_1734
Phytoene synthase.
 
 
 0.874
lysK
Peptidase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.
     
 0.863
argD
Acetylornithine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
     
 0.859
lysX
Conserved Archaeal protein; Catalyzes the ATP-dependent formation of a covalent bond between the amino group of alpha-aminoadipate (AAA) and the gamma- carboxyl group of the C-terminal glutamate residue in LysW. Belongs to the RimK family. LysX subfamily.
       0.848
tatC
Translocase 6TM; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes.
 
   
 0.836
rps8e
30S ribosomal protein S8E.
  
    0.810
Your Current Organism:
Sulfolobus acidocaldarius DSM 639
NCBI taxonomy Id: 330779
Other names: S. acidocaldarius DSM 639, Sulfolobus acidocaldarius ATCC 33909, Sulfolobus acidocaldarius NCIB 11770
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