node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Saci_0011 | rgy | Saci_0011 | Saci_0839 | Universally conserved protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | 0.462 |
Saci_0046 | rgy | Saci_0046 | Saci_0839 | Conserved Archaeal protein. | Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | 0.568 |
Saci_0546 | rgy | Saci_0546 | Saci_0839 | Conserved protein. | Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | 0.495 |
Saci_0546 | taw3 | Saci_0546 | Saci_1603 | Conserved protein. | Conserved Archaeal protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | 0.476 |
Saci_0840 | rgy | Saci_0840 | Saci_0839 | Conserved protein. | Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | 0.851 |
Saci_1796 | rgy | Saci_1796 | Saci_0839 | Hypothetical protein. | Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | 0.476 |
Saci_1797 | Saci_2321 | Saci_1797 | Saci_2321 | Hypothetical membrane protein. | Glutamine amidotransferase class-II domain protein. | 0.732 |
Saci_1797 | rgy | Saci_1797 | Saci_0839 | Hypothetical membrane protein. | Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | 0.476 |
Saci_2321 | Saci_1797 | Saci_2321 | Saci_1797 | Glutamine amidotransferase class-II domain protein. | Hypothetical membrane protein. | 0.732 |
Saci_2321 | rgy | Saci_2321 | Saci_0839 | Glutamine amidotransferase class-II domain protein. | Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | 0.474 |
rgy | Saci_0011 | Saci_0839 | Saci_0011 | Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | Universally conserved protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | 0.462 |
rgy | Saci_0046 | Saci_0839 | Saci_0046 | Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | Conserved Archaeal protein. | 0.568 |
rgy | Saci_0546 | Saci_0839 | Saci_0546 | Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | Conserved protein. | 0.495 |
rgy | Saci_0840 | Saci_0839 | Saci_0840 | Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | Conserved protein. | 0.851 |
rgy | Saci_1796 | Saci_0839 | Saci_1796 | Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | Hypothetical protein. | 0.476 |
rgy | Saci_1797 | Saci_0839 | Saci_1797 | Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | Hypothetical membrane protein. | 0.476 |
rgy | Saci_2321 | Saci_0839 | Saci_2321 | Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | Glutamine amidotransferase class-II domain protein. | 0.474 |
rgy | sucC | Saci_0839 | Saci_1265 | Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | succinyl-CoA synthetase beta chain. | 0.787 |
rgy | taw3 | Saci_0839 | Saci_1603 | Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | Conserved Archaeal protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | 0.523 |
rgy | top1 | Saci_0839 | Saci_1371 | Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | DNA topoisomerase I family A. | 0.554 |