node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Saci_1308 | dys | Saci_1308 | Saci_1316 | Short chain dehydrogenase; Similar to sp:P25529 7-alpha-hydroxysteroid dehydrogenase (EC 1.1.1.159). | Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | 0.587 |
Saci_1308 | eif5a | Saci_1308 | Saci_1311 | Short chain dehydrogenase; Similar to sp:P25529 7-alpha-hydroxysteroid dehydrogenase (EC 1.1.1.159). | Translation initiation factor 5A; Functions by promoting the formation of the first peptide bond. | 0.836 |
Saci_1308 | rtcB | Saci_1308 | Saci_1317 | Short chain dehydrogenase; Similar to sp:P25529 7-alpha-hydroxysteroid dehydrogenase (EC 1.1.1.159). | Universally conserved protein; Uncharacterized protein family UPF002; Belongs to the RtcB family. | 0.425 |
Saci_1308 | top6A | Saci_1308 | Saci_1314 | Short chain dehydrogenase; Similar to sp:P25529 7-alpha-hydroxysteroid dehydrogenase (EC 1.1.1.159). | DNA topoisomerase VI, subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. | 0.511 |
Saci_1308 | top6B | Saci_1308 | Saci_1315 | Short chain dehydrogenase; Similar to sp:P25529 7-alpha-hydroxysteroid dehydrogenase (EC 1.1.1.159). | DNA topoisomerase VI subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. | 0.417 |
argS | dys | Saci_1396 | Saci_1316 | arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | 0.629 |
argS | eif5a | Saci_1396 | Saci_1311 | arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Translation initiation factor 5A; Functions by promoting the formation of the first peptide bond. | 0.694 |
argS | flpA | Saci_1396 | Saci_1346 | arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Fribrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | 0.561 |
argS | pheS | Saci_1396 | Saci_1511 | arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | phenylalanyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. | 0.864 |
argS | speE | Saci_1396 | Saci_0643 | arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.577 |
dys | Saci_1308 | Saci_1316 | Saci_1308 | Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | Short chain dehydrogenase; Similar to sp:P25529 7-alpha-hydroxysteroid dehydrogenase (EC 1.1.1.159). | 0.587 |
dys | argS | Saci_1316 | Saci_1396 | Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.629 |
dys | eif5a | Saci_1316 | Saci_1311 | Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | Translation initiation factor 5A; Functions by promoting the formation of the first peptide bond. | 0.998 |
dys | flpA | Saci_1316 | Saci_1346 | Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | Fribrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | 0.712 |
dys | pheS | Saci_1316 | Saci_1511 | Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | phenylalanyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. | 0.602 |
dys | rpl10e | Saci_1316 | Saci_0176 | Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | 50S ribosomal protein L10E; Belongs to the universal ribosomal protein uL16 family. | 0.623 |
dys | rtcB | Saci_1316 | Saci_1317 | Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | Universally conserved protein; Uncharacterized protein family UPF002; Belongs to the RtcB family. | 0.869 |
dys | speE | Saci_1316 | Saci_0643 | Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.608 |
dys | top6A | Saci_1316 | Saci_1314 | Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | DNA topoisomerase VI, subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. | 0.969 |
dys | top6B | Saci_1316 | Saci_1315 | Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | DNA topoisomerase VI subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. | 0.814 |