STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
atpBV-type ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (452 aa)    
Predicted Functional Partners:
Saci_0846
Conserved protein.
  
 0.999
Saci_1545
Conserved protein; Belongs to the V-ATPase 116 kDa subunit family.
 
 0.999
Saci_1546
Conserved protein; Identification based on homology with Sulfolobus solfataricus and Sulfolobus tokodaii; upstream TA rich sequence was found.
  
 0.999
atpE
Conserved protein; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
 0.999
atpA
V-type ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit; Belongs to the ATPase alpha/beta chains family.
 
0.999
atpD
V-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
 0.999
atpP
Membrane-associated ATPase C chain; The C chain is a proteolipid, and one of the membranous subunits of the nonenzymatic component of the Sul-ATPase complex. Belongs to the V-ATPase proteolipid subunit family.
 
 0.999
ppa
Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
   
 
 0.943
fusA
Elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...]
 
 
 0.867
Saci_1281
Conserved putative ATP binding protein; Members of family are found in a range of archaea and eukaryotes and have hypothesised ATP binding activity.
   
 0.800
Your Current Organism:
Sulfolobus acidocaldarius DSM 639
NCBI taxonomy Id: 330779
Other names: S. acidocaldarius DSM 639, Sulfolobus acidocaldarius ATCC 33909, Sulfolobus acidocaldarius NCIB 11770
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