node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Saci_1594 | carB | Saci_1594 | Saci_1620 | Hypothetical protein; Similar to gi:15897528. | Carbamoyl-phosphate synthase L chain. | 0.996 |
Saci_1594 | pyrA | Saci_1594 | Saci_1619 | Hypothetical protein; Similar to gi:15897528. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.993 |
Saci_1594 | pyrB | Saci_1594 | Saci_1596 | Hypothetical protein; Similar to gi:15897528. | Aspartate carbamoyltransferase. | 0.998 |
Saci_1594 | pyrC | Saci_1594 | Saci_1593 | Hypothetical protein; Similar to gi:15897528. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.988 |
Saci_1594 | pyrD | Saci_1594 | Saci_1592 | Hypothetical protein; Similar to gi:15897528. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.999 |
Saci_1594 | pyrE | Saci_1594 | Saci_1597 | Hypothetical protein; Similar to gi:15897528. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.997 |
Saci_1594 | pyrF | Saci_1594 | Saci_1598 | Hypothetical protein; Similar to gi:15897528. | Orotidine 5'-phosphate decarboxylase. | 0.997 |
Saci_1594 | pyrI | Saci_1594 | Saci_1595 | Hypothetical protein; Similar to gi:15897528. | Aspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.900 |
aspB | purA | Saci_1428 | Saci_0709 | Aspartate aminotransferase; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.935 |
aspB | pyrB | Saci_1428 | Saci_1596 | Aspartate aminotransferase; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Aspartate carbamoyltransferase. | 0.923 |
aspB | pyrC | Saci_1428 | Saci_1593 | Aspartate aminotransferase; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.447 |
aspB | pyrD | Saci_1428 | Saci_1592 | Aspartate aminotransferase; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.478 |
aspB | pyrI | Saci_1428 | Saci_1595 | Aspartate aminotransferase; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Aspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.900 |
carB | Saci_1594 | Saci_1620 | Saci_1594 | Carbamoyl-phosphate synthase L chain. | Hypothetical protein; Similar to gi:15897528. | 0.996 |
carB | purA | Saci_1620 | Saci_0709 | Carbamoyl-phosphate synthase L chain. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.874 |
carB | pyrA | Saci_1620 | Saci_1619 | Carbamoyl-phosphate synthase L chain. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.999 |
carB | pyrB | Saci_1620 | Saci_1596 | Carbamoyl-phosphate synthase L chain. | Aspartate carbamoyltransferase. | 0.999 |
carB | pyrC | Saci_1620 | Saci_1593 | Carbamoyl-phosphate synthase L chain. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.999 |
carB | pyrD | Saci_1620 | Saci_1592 | Carbamoyl-phosphate synthase L chain. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.997 |
carB | pyrE | Saci_1620 | Saci_1597 | Carbamoyl-phosphate synthase L chain. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.997 |