node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Saci_0546 | rgy | Saci_0546 | Saci_0839 | Conserved protein. | Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | 0.495 |
Saci_0546 | taw3 | Saci_0546 | Saci_1603 | Conserved protein. | Conserved Archaeal protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | 0.476 |
Saci_0559 | taw1 | Saci_0559 | Saci_1331 | Conserved Archaeal protein. | Conserved protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). | 0.434 |
Saci_0559 | taw3 | Saci_0559 | Saci_1603 | Conserved Archaeal protein. | Conserved Archaeal protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | 0.473 |
Saci_0833 | spt4 | Saci_0833 | Saci_0835 | Conserved protein. | Conserved Archaeal protein; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. | 0.851 |
Saci_0833 | taw3 | Saci_0833 | Saci_1603 | Conserved protein. | Conserved Archaeal protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | 0.540 |
Saci_0833 | tmcA-2 | Saci_0833 | Saci_0428 | Conserved protein. | Hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). | 0.541 |
Saci_1339 | taw3 | Saci_1339 | Saci_1603 | Conserved Archaeal protein. | Conserved Archaeal protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | 0.546 |
Saci_1602 | taw3 | Saci_1602 | Saci_1603 | Hypothetical protein. | Conserved Archaeal protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | 0.601 |
rgy | Saci_0546 | Saci_0839 | Saci_0546 | Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | Conserved protein. | 0.495 |
rgy | taw3 | Saci_0839 | Saci_1603 | Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | Conserved Archaeal protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | 0.523 |
spt4 | Saci_0833 | Saci_0835 | Saci_0833 | Conserved Archaeal protein; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. | Conserved protein. | 0.851 |
spt4 | taw3 | Saci_0835 | Saci_1603 | Conserved Archaeal protein; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. | Conserved Archaeal protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | 0.486 |
taw1 | Saci_0559 | Saci_1331 | Saci_0559 | Conserved protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). | Conserved Archaeal protein. | 0.434 |
taw1 | taw3 | Saci_1331 | Saci_1603 | Conserved protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). | Conserved Archaeal protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | 0.882 |
taw3 | Saci_0546 | Saci_1603 | Saci_0546 | Conserved Archaeal protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | Conserved protein. | 0.476 |
taw3 | Saci_0559 | Saci_1603 | Saci_0559 | Conserved Archaeal protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | Conserved Archaeal protein. | 0.473 |
taw3 | Saci_0833 | Saci_1603 | Saci_0833 | Conserved Archaeal protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | Conserved protein. | 0.540 |
taw3 | Saci_1339 | Saci_1603 | Saci_1339 | Conserved Archaeal protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | Conserved Archaeal protein. | 0.546 |
taw3 | Saci_1602 | Saci_1603 | Saci_1602 | Conserved Archaeal protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | Hypothetical protein. | 0.601 |