STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAC1-1Nuclear distribution protein PAC1-1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (446 aa)    
Predicted Functional Partners:
UREG_05232
Dynein heavy chain.
    
 0.940
PAC1-2
Nuclear distribution protein PAC1-2; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs.
  
  
 
0.902
UREG_02722
Patatin-like phospholipase domain-containing protein; Lipid hydrolase; Belongs to the PLPL family.
     
  0.900
UREG_03097
Uncharacterized protein; Belongs to the membrane-bound acyltransferase family.
     
  0.900
UREG_06306
Lysophospholipase.
     
  0.900
UREG_01514
Uncharacterized protein.
   
 0.802
UREG_00788
NUDE_C domain-containing protein.
    
 
 0.764
UREG_06531
CAP-Gly domain-containing protein.
    
 0.759
UREG_06638
Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
    
 0.747
UREG_02729
Nuclear movement protein nudC.
    
 0.691
Your Current Organism:
Uncinocarpus reesii
NCBI taxonomy Id: 336963
Other names: U. reesii 1704, Uncinocarpus reesii 1704
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