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STRINGSTRING
cca protein (Nitrosomonas eutropha) - STRING interaction network
"cca" - Multifunctional CCA protein in Nitrosomonas eutropha
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second shell of interactors
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filled nodes:
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ccaMultifunctional CCA protein; Catalyzes the addition and repair of the essential 3’- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2’- nucleotidase and 2’,3’-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3’-CCA terminus degraded by intracellular RNases (412 aa)    
Predicted Functional Partners:
Neut_0502
PFAM- Lytic transglycosylase, catalytic; KEGG- neu-NE1615 SLT domain (635 aa)
 
        0.898
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (906 aa)
   
   
  0.710
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3’- to 5’-direction (705 aa)
   
 
  0.582
Neut_0498
PFAM- ribonuclease II; KEGG- neu-NE1625 ribonuclease II domain (619 aa)
   
 
  0.552
hfq
RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (80 aa)
       
 
  0.514
birA
Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor (329 aa)
         
  0.499
Neut_0501
PFAM- Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; KEGG- neu-NE1616 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family (447 aa)
   
        0.500
Neut_0272
ATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (90 aa)
   
          0.493
rnr
Ribonuclease R; 3’-5’ exoribonuclease that releases 5’-nucleoside monophosphates and is involved in maturation of structured RNAs (734 aa)
   
 
  0.484
tilS
tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (418 aa)
 
   
  0.462
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha C91, Nitrosomonas eutropha, Nitrosomonas eutropha C91, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
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