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nth protein (Nitrosomonas eutropha) - STRING interaction network
"nth" - Endonuclease III in Nitrosomonas eutropha
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3’ to the AP site by a beta-elimination, leaving a 3’-terminal unsaturated sugar and a product with a terminal 5’-phosphate (219 aa)    
Predicted Functional Partners:
Neut_0645
Electron transport complex, RnfABCDGE type, B subunit; Part of a membrane complex involved in electron transport (218 aa)
   
   
  0.900
pyrD
Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily (342 aa)
              0.879
aat
Leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (234 aa)
              0.854
ate
Putative arginyl-tRNA--protein transferase; May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate (237 aa)
              0.854
Neut_0691
KEGG- neu-NE2192 exodeoxyribonuclease III-exodeoxyribonuclease III xth; TIGRFAM- exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM- Endonuclease/exonuclease/phosphatase (257 aa)
 
 
 
  0.834
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (906 aa)
   
 
  0.796
Neut_1346
Transcriptional regulator Ada / DNA-O6-methylguanine--protein-cysteine S-methyltransferase; TIGRFAM- methylated-DNA--protein-cysteine methyltransferase; PFAM- helix-turn-helix- domain containing protein, AraC type; methylated-DNA-[protein]-cysteine S-methyltransferase; KEGG- lic-LIC13402 methylated-DNA--protein-cysteine methyltransferase transcription regulator (281 aa)
         
  0.737
Neut_1221
DNA-O6-methylguanine--protein-cysteine S-methyltransferase; PFAM- helix-turn-helix- domain containing protein, AraC type; HhH-GPD family protein; Ada, metal-binding domain protein; AlkA domain protein; KEGG- pcu-pc1834 putative DNA-3-methyladenine glycosidase II (477 aa)
   
 
  0.711
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (608 aa)
 
 
  0.688
recA
Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (343 aa)
   
 
  0.620
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha C91, Nitrosomonas eutropha, Nitrosomonas eutropha C91, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
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