STRINGSTRING
mpl protein (Nitrosomonas eutropha) - STRING interaction network
"mpl" - UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase in Nitrosomonas eutropha
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mplUDP-N-acetylmuramate-L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate (460 aa)    
Predicted Functional Partners:
Neut_1402
Cyanophycin synthetase (862 aa)
   
 
  0.893
Neut_1401
Cyanophycin synthetase (765 aa)
   
 
  0.893
Neut_0778
DNA polymerase I (906 aa)
     
 
  0.832
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (417 aa)
 
 
  0.821
murG
Undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (370 aa)
   
  0.817
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (457 aa)
 
 
  0.815
Neut_0252
Peptidoglycan glycosyltransferase (579 aa)
 
 
  0.809
Neut_0251
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase (520 aa)
 
 
  0.798
murD
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (470 aa)
 
 
  0.794
Neut_0535
N-acetyl-anhydromuranmyl-L-alanine amidase (181 aa)
 
     
  0.793
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha, N. eutropha C91, Nitrosomonas eutropha, Nitrosomonas eutropha C91, Nitrosomonas eutropha Koops et al. 2001, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
Server load: low (11%) [HD]