• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
purA protein (Nitrosomonas eutropha) - STRING interaction network
"purA" - Adenylosuccinate synthetase in Nitrosomonas eutropha
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family (432 aa)    
Predicted Functional Partners:
Neut_0410
KEGG- neu-NE1951 adenylosuccinate lyase; TIGRFAM- adenylosuccinate lyase; PFAM- fumarate lyase; Adenylosuccinate lyase C-terminal domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily (458 aa)
 
 
  0.988
purH
Bifunctional purine biosynthesis protein PurH; KEGG- neu-NE0876 probable phosphoribosylaminoimidazolecarboxamide formyltransferase and IMP cyclodydrolase transmembrane protein; TIGRFAM- phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM- AICARFT/IMPCHase bienzyme; MGS domain protein (520 aa)
 
  0.988
guaB
Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family (487 aa)
 
 
  0.985
pyrB
TIGRFAM- aspartate carbamoyltransferase; PFAM- aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; KEGG- neu-NE1665 aspartate carbamoyltransferase (catalytic chain) protein; Belongs to the ATCase/OTCase family (316 aa)
 
 
  0.960
argG
PFAM- argininosuccinate synthase; KEGG- neu-NE1437 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily (404 aa)
   
 
  0.945
Neut_2004
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate (527 aa)
         
  0.909
Neut_1735
PFAM- glutamine amidotransferase, class-II; asparagine synthase; KEGG- lpl-lp_0980 asparagine synthase (glutamine-hydrolysing) (606 aa)
     
 
    0.907
Neut_1419
PFAM- asparagine synthase; KEGG- neu-NE1127 asparagine synthase (615 aa)
     
 
    0.907
Neut_0901
KEGG- neu-NE1795 glutamine amidotransferase class-II-asparagine synthase; TIGRFAM- asparagine synthase (glutamine-hydrolyzing); PFAM- glutamine amidotransferase, class-II; asparagine synthase (644 aa)
     
 
    0.907
surE
5’-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5’-monophosphates; Belongs to the SurE nucleotidase family (247 aa)
   
 
    0.907
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha C91, Nitrosomonas eutropha, Nitrosomonas eutropha C91, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
Server load: low (7%) [HD]