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Neut_1155 protein (Nitrosomonas eutropha) - STRING interaction network
"Neut_1155" - TIGRFAM: FolC bifunctional protein in Nitrosomonas eutropha
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Neut_1155TIGRFAM- FolC bifunctional protein; PFAM- cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG- neu-NE0696 cytoplasmic peptidoglycan synthetases, C-terminal; Belongs to the folylpolyglutamate synthase family (428 aa)    
Predicted Functional Partners:
Neut_0999
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives (300 aa)
 
  0.995
Neut_1020
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (176 aa)
   
  0.957
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (416 aa)
   
  0.939
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA; Belongs to the AccD/PCCB family (296 aa)
 
   
  0.937
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2’-deoxyuridine- 5’-monophosphate (dUMP) to 2’-deoxythymidine-5’-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis (264 aa)
     
 
  0.907
Neut_2295
KEGG- neu-NE0070 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; TIGRFAM- 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM- 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK (170 aa)
 
   
  0.883
Neut_1156
PFAM- Sporulation domain protein; KEGG- neu-NE0697 possible transmembrane protein (223 aa)
   
   
  0.873
Neut_1157
PFAM- Colicin V production protein; KEGG- neu-NE0698 colicin V production protein (164 aa)
   
   
  0.870
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family (505 aa)
 
   
  0.771
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (277 aa)
 
   
  0.757
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha C91, Nitrosomonas eutropha, Nitrosomonas eutropha C91, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
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