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Neut_1220 protein (Nitrosomonas eutropha) - STRING interaction network
"Neut_1220" - methylated-DNA--protein-cysteine methyltransferase in Nitrosomonas eutropha
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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[Homology]
Score
Neut_1220methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction- the enzyme is irreversibly inactivated (167 aa)    
Predicted Functional Partners:
Neut_1221
AraC family transcriptional regulator (477 aa)
 
  0.993
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth (749 aa)
     
 
  0.785
Neut_0778
DNA polymerase I (906 aa)
     
 
  0.693
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3’ to the AP site by a beta-elimination, leaving a 3’-terminal unsaturated sugar and a product with a terminal 5’-phosphate (219 aa)
         
  0.559
rpoH
RNA polymerase factor sigma-32 (280 aa)
     
 
  0.551
xerD
Tyrosine recombinase XerD (305 aa)
     
      0.480
Neut_1222
Hypothetical protein (80 aa)
              0.474
Neut_1349
2OG-Fe(II) oxygenase (208 aa)
   
   
  0.469
pheT
phenylalanyl-tRNA synthetase subunit beta (792 aa)
              0.459
Neut_1215
Helicase c2 (648 aa)
   
        0.437
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha, N. eutropha C91, Nitrosomonas eutropha, Nitrosomonas eutropha C91, Nitrosomonas eutropha Koops et al. 2001, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
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