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leuA protein (Nitrosomonas eutropha) - STRING interaction network
"leuA" - 2-isopropylmalate synthase in Nitrosomonas eutropha
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (510 aa)    
Predicted Functional Partners:
leuC
Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (470 aa)
 
  0.996
leuD
Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (212 aa)
 
 
  0.992
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (356 aa)
 
 
  0.988
ilvD
Dihydroxy-acid dehydratase (557 aa)
 
 
  0.983
Neut_1262
Acetolactate synthase large subunit (567 aa)
 
 
  0.983
Neut_2005
Branched-chain amino acid aminotransferase (306 aa)
   
  0.967
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (655 aa)
   
 
  0.919
Neut_0610
Beta-ketothiolase (392 aa)
   
 
  0.916
Neut_1261
Acetolactate synthase 3 regulatory subunit (163 aa)
   
 
  0.913
Neut_1995
Phosphate acetyltransferase; Involved in acetate metabolism (709 aa)
         
  0.912
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha, N. eutropha C91, Nitrosomonas eutropha, Nitrosomonas eutropha C91, Nitrosomonas eutropha Koops et al. 2001, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
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