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glnE protein (Nitrosomonas eutropha) - STRING interaction network
"glnE" - Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme in Nitrosomonas eutropha
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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glnEBifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory regi [...] (929 aa)    
Predicted Functional Partners:
Neut_1231
KEGG- neu-NE0504 glutamine synthetase type I, GlnA; TIGRFAM- glutamine synthetase, type I; PFAM- glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp (468 aa)
 
     
  0.837
Neut_0802
KEGG- nha-Nham_4043 nitrogen regulatory protein P-II (GlnB, GlnK); Belongs to the P(II) protein family (108 aa)
 
 
  0.767
Neut_1634
PFAM- alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG- neu-NE0772 bacterioferritin comigratory protein (151 aa)
            0.750
Neut_1265
TIGRFAM- conserved hypothetical protein; KEGG- neu-NE1328 possible transmembrane protein (1296 aa)
              0.647
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme (476 aa)
     
   
  0.552
Neut_1264
PFAM- Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG- neu-NE1327 carbon-nitrogen hydrolase (287 aa)
         
  0.522
Neut_1263
Uncharacterized protein; PFAM- peptidase U62, modulator of DNA gyrase; KEGG- neu-NE1326 putative modulator of DNA gyrase (483 aa)
   
        0.521
nadE
Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source (535 aa)
         
  0.502
lptD
LPS-assembly protein LptD; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane (725 aa)
   
          0.464
lptA
Lipopolysaccharide export system protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane (183 aa)
 
        0.417
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha C91, Nitrosomonas eutropha, Nitrosomonas eutropha C91, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
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