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Neut_1384 protein (Nitrosomonas eutropha) - STRING interaction network
"Neut_1384" - ATP-dependent metalloprotease FtsH in Nitrosomonas eutropha
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Neut_1384ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (617 aa)    
Predicted Functional Partners:
grpE
Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] (196 aa)
   
  0.819
Neut_0970
ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (791 aa)
     
 
  0.800
Neut_0201
ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (807 aa)
     
 
  0.800
Neut_0908
peptidyl-tRNA hydrolase (617 aa)
   
   
  0.783
Neut_0907
peptidyl-tRNA hydrolase (630 aa)
   
   
  0.783
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) (252 aa)
 
   
  0.757
ftsJ
Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2’-O position of the ribose in the fully assembled 50S ribosomal subunit (206 aa)
 
 
  0.732
dnaK
Molecular chaperone DnaK; Acts as a chaperone (647 aa)
   
  0.702
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (547 aa)
     
 
  0.696
clpB
ATPase; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE (863 aa)
 
 
  0.692
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha, N. eutropha C91, Nitrosomonas eutropha, Nitrosomonas eutropha C91, Nitrosomonas eutropha Koops et al. 2001, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
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