STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folE2GTP cyclohydrolase I; Converts GTP to 7,8-dihydroneopterin triphosphate. (267 aa)    
Predicted Functional Partners:
Neut_1286
PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: neu:NE1517 6-pyruvoyl tetrahydropterin synthase.
 
  
 0.938
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
 0.908
Neut_0615
Dihydroneopterin triphosphate pyrophosphatase; PFAM: NUDIX hydrolase; KEGG: neu:NE2253 dATP pyrophosphohydrolase.
     
  0.900
Neut_2295
KEGG: neu:NE0070 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK.
    
 0.882
Neut_0979
PFAM: pyruvate kinase; KEGG: nmu:Nmul_A1507 pyruvate kinase; Belongs to the pyruvate kinase family.
 
  
  0.832
Neut_1580
PFAM: pyruvate kinase; KEGG: neu:NE0325 pyruvate kinase; Belongs to the pyruvate kinase family.
 
  
  0.829
Neut_1118
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: neu:NE1847 guanylate cyclase.
     
  0.800
Neut_1601
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
  0.800
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
  0.800
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
       0.588
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha C91, Nitrosomonas eutropha C91, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
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