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xseA protein (Nitrosomonas eutropha) - STRING interaction network
"xseA" - Exodeoxyribonuclease 7 large subunit in Nitrosomonas eutropha
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
xseAExodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family (448 aa)    
Predicted Functional Partners:
xseB
Exodeoxyribonuclease 7 small subunit; Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family (103 aa)
 
  0.997
Neut_1204
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems (212 aa)
            0.831
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (906 aa)
 
     
  0.743
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (1300 aa)
   
   
  0.696
ruvA
Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (194 aa)
 
   
  0.685
Neut_1511
PFAM- protein of unknown function DUF423; KEGG- neu-NE1173 hypothetical protein (126 aa)
              0.642
Neut_0131
Exonuclease RecJ; TIGRFAM- single-stranded-DNA-specific exonuclease RecJ; PFAM- phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1; KEGG- neu-NE0010 single-stranded-DNA-specific exonuclease (589 aa)
 
   
  0.635
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3’ invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA’s homology-searching function (449 aa)
   
   
  0.591
Neut_2470
Urea amidolyase related protein; KEGG- neu-NE2420 biotin / lipoyl attachment-carbamoyl-phosphate synthase-DUF183; TIGRFAM- urea amidolyase related protein; PFAM- biotin/lipoyl attachment domain-containing protein; Allophanate hydrolase subunit 2; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein (1206 aa)
   
   
  0.587
recA
Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (343 aa)
         
  0.584
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha C91, Nitrosomonas eutropha, Nitrosomonas eutropha C91, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
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