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thiE protein (Nitrosomonas eutropha) - STRING interaction network
"thiE" - Thiamine-phosphate synthase in Nitrosomonas eutropha
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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thiEThiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP); Belongs to the thiamine-phosphate synthase family (212 aa)    
Predicted Functional Partners:
Neut_1539
PFAM- Phosphomethylpyrimidine kinase type-1; KEGG- neu-NE1425 putative phosphomethylpyrimidine kinase (280 aa)
 
  0.999
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family (328 aa)
 
  0.974
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (268 aa)
 
   
  0.961
hemL
TIGRFAM- glutamate-1-semialdehyde-2,1-aminomutase; PFAM- aminotransferase class-III; KEGG- neu-NE1423 glutamate-1-semialdehyde 2,1-aminomutase protein (427 aa)
 
   
  0.941
surE
5’-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5’-monophosphates; Belongs to the SurE nucleotidase family (247 aa)
     
 
    0.905
thiC
Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (632 aa)
 
   
  0.903
rsgA
Small ribosomal subunit biogenesis GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit (309 aa)
     
 
    0.901
Neut_0653
PFAM- NUDIX hydrolase; thiamine monophosphate synthase; KEGG- neu-NE2215 NUDIX hydrolase / thiamine phosphate synthase; Belongs to the Nudix hydrolase family (312 aa)
 
        0.790
Neut_1540
PFAM- Rubredoxin-type Fe(Cys)4 protein; KEGG- neu-NE1426 rubredoxin-rubredoxin-type Fe(Cys)4 protein (62 aa)
              0.730
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family (369 aa)
 
   
  0.676
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha C91, Nitrosomonas eutropha, Nitrosomonas eutropha C91, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
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