• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
Neut_1541 protein (Nitrosomonas eutropha) - STRING interaction network
"Neut_1541" - Lactoylglutathione lyase in Nitrosomonas eutropha
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Neut_1541Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione (129 aa)    
Predicted Functional Partners:
gloB
Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (255 aa)
 
 
  0.966
Neut_1540
PFAM- Rubredoxin-type Fe(Cys)4 protein; KEGG- neu-NE1426 rubredoxin-rubredoxin-type Fe(Cys)4 protein (62 aa)
   
   
  0.866
ilvA
L-threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (503 aa)
       
  0.841
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate; Belongs to the TrpA family (274 aa)
     
 
  0.814
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (399 aa)
     
 
  0.813
Neut_1760
L-serine ammonia-lyase; KEGG- neu-NE0380 iron-sulfur-dependent L-serine dehydratase single chain form; TIGRFAM- L-serine dehydratase 1; PFAM- serine dehydratase alpha chain; serine dehydratase beta chain (461 aa)
         
    0.800
Neut_0829
TIGRFAM- glutaredoxin-like protein; PFAM- glutaredoxin; KEGG- neu-NE1911 glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily (102 aa)
   
      0.656
thiE
Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP); Belongs to the thiamine-phosphate synthase family (212 aa)
              0.635
Neut_1539
PFAM- Phosphomethylpyrimidine kinase type-1; KEGG- neu-NE1425 putative phosphomethylpyrimidine kinase (280 aa)
              0.627
Neut_1549
N-acetylneuraminate synthase; PFAM- CBS domain containing protein; Xylose isomerase domain protein TIM barrel; N-acetylneuraminic acid synthase, N-terminal domain; KEGG- neu-NE1570 type III antifreeze protein-CBS domain-NeuB family (749 aa)
   
 
  0.623
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha C91, Nitrosomonas eutropha, Nitrosomonas eutropha C91, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
Server load: low (7%) [HD]