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metE protein (Nitrosomonas eutropha) - STRING interaction network
"metE" - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase in Nitrosomonas eutropha
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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metE5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (769 aa)    
Predicted Functional Partners:
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme (387 aa)
   
  0.993
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (478 aa)
   
 
  0.992
Neut_1891
KEGG- neu-NE0661 5,10-methylenetetrahydrofolate reductase oxidoreductase protein; TIGRFAM- 5,10-methylenetetrahydrofolate reductase; PFAM- methylenetetrahydrofolate reductase (284 aa)
 
  0.982
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide (391 aa)
   
 
  0.963
Neut_0500
TIGRFAM- methionine synthase; PFAM- dihydropteroate synthase, DHPS; homocysteine S-methyltransferase; Methionine synthase, B12-binding module, cap domain protein; Vitamin B12 dependent methionine synthase, activation region; cobalamin B12-binding domain protein; KEGG- neu-NE1623 MetH methionine synthase I, cobalamin-binding domain (1237 aa)
   
 
  0.948
metG
Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (701 aa)
   
  0.946
Neut_0424
O-acetylhomoserine sulfhydrolase; KEGG- neu-NE1697 Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; TIGRFAM- O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM- Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase (424 aa)
   
 
  0.932
Neut_0837
PFAM- aminotransferase, class I and II; KEGG- neu-NE2400 aminotransferases class-I (393 aa)
       
  0.907
Neut_1554
Transcriptional regulator, LysR family; PFAM- regulatory protein, LysR; LysR, substrate-binding; KEGG- neu-NE1435 bacterial regulatory protein, LysR family (311 aa)
 
   
  0.868
ilvA
L-threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (503 aa)
   
 
  0.835
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha C91, Nitrosomonas eutropha, Nitrosomonas eutropha C91, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
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