node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Neut_0410 | Neut_0861 | Neut_0410 | Neut_0861 | KEGG: neu:NE1951 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase C-terminal domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: neu:NE2373 citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | 0.800 |
Neut_0410 | Neut_2045 | Neut_0410 | Neut_2045 | KEGG: neu:NE1951 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase C-terminal domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: neu:NE1730 isocitrate dehydrogenase [NADP] oxidoreductase protein. | 0.828 |
Neut_0410 | mdh | Neut_0410 | Neut_1633 | KEGG: neu:NE1951 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase C-terminal domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.852 |
Neut_0501 | Neut_0861 | Neut_0501 | Neut_0861 | Glutamate dehydrogenase (NADP); PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; KEGG: neu:NE1616 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | KEGG: neu:NE2373 citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | 0.894 |
Neut_0501 | Neut_1083 | Neut_0501 | Neut_1083 | Glutamate dehydrogenase (NADP); PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; KEGG: neu:NE1616 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | PFAM: aminotransferase, class I and II; KEGG: neu:NE0786 aminotransferases class-I. | 0.909 |
Neut_0501 | Neut_2045 | Neut_0501 | Neut_2045 | Glutamate dehydrogenase (NADP); PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; KEGG: neu:NE1616 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: neu:NE1730 isocitrate dehydrogenase [NADP] oxidoreductase protein. | 0.962 |
Neut_0501 | mdh | Neut_0501 | Neut_1633 | Glutamate dehydrogenase (NADP); PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; KEGG: neu:NE1616 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.873 |
Neut_0596 | Neut_0861 | Neut_0596 | Neut_0861 | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); PFAM: malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: neu:NE0438 putative malate oxidoreductase (malic enzyme). | KEGG: neu:NE2373 citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | 0.885 |
Neut_0596 | Neut_2045 | Neut_0596 | Neut_2045 | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); PFAM: malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: neu:NE0438 putative malate oxidoreductase (malic enzyme). | TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: neu:NE1730 isocitrate dehydrogenase [NADP] oxidoreductase protein. | 0.403 |
Neut_0596 | fumC | Neut_0596 | Neut_2124 | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); PFAM: malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: neu:NE0438 putative malate oxidoreductase (malic enzyme). | Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.956 |
Neut_0596 | mdh | Neut_0596 | Neut_1633 | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); PFAM: malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: neu:NE0438 putative malate oxidoreductase (malic enzyme). | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.957 |
Neut_0596 | sucC-2 | Neut_0596 | Neut_0606 | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); PFAM: malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: neu:NE0438 putative malate oxidoreductase (malic enzyme). | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.854 |
Neut_0596 | sucD-2 | Neut_0596 | Neut_0605 | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); PFAM: malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: neu:NE0438 putative malate oxidoreductase (malic enzyme). | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.833 |
Neut_0861 | Neut_0410 | Neut_0861 | Neut_0410 | KEGG: neu:NE2373 citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | KEGG: neu:NE1951 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase C-terminal domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.800 |
Neut_0861 | Neut_0501 | Neut_0861 | Neut_0501 | KEGG: neu:NE2373 citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | Glutamate dehydrogenase (NADP); PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; KEGG: neu:NE1616 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.894 |
Neut_0861 | Neut_0596 | Neut_0861 | Neut_0596 | KEGG: neu:NE2373 citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); PFAM: malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: neu:NE0438 putative malate oxidoreductase (malic enzyme). | 0.885 |
Neut_0861 | Neut_1083 | Neut_0861 | Neut_1083 | KEGG: neu:NE2373 citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | PFAM: aminotransferase, class I and II; KEGG: neu:NE0786 aminotransferases class-I. | 0.878 |
Neut_0861 | Neut_2045 | Neut_0861 | Neut_2045 | KEGG: neu:NE2373 citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: neu:NE1730 isocitrate dehydrogenase [NADP] oxidoreductase protein. | 0.965 |
Neut_0861 | fumC | Neut_0861 | Neut_2124 | KEGG: neu:NE2373 citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.912 |
Neut_0861 | mdh | Neut_0861 | Neut_1633 | KEGG: neu:NE2373 citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.996 |