node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Neut_0452 | carA | Neut_0452 | Neut_0454 | TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: neu:NE1664 dihydroorotase. | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain; KEGG: neu:NE1662 carbamoyl-phosphate synthase (small chain) protein; Belongs to the CarA family. | 0.997 |
Neut_0452 | carB | Neut_0452 | Neut_0455 | TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: neu:NE1664 dihydroorotase. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: neu:NE1661 carbamoyl-phosphate synthase:methylglyoxal synthase-like domain; Belongs to the CarB family. | 0.997 |
Neut_0452 | guaA | Neut_0452 | Neut_2251 | TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: neu:NE1664 dihydroorotase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.489 |
Neut_0452 | purL | Neut_0452 | Neut_0140 | TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: neu:NE1664 dihydroorotase. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.537 |
Neut_0452 | pyrB | Neut_0452 | Neut_0451 | TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: neu:NE1664 dihydroorotase. | TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; KEGG: neu:NE1665 aspartate carbamoyltransferase (catalytic chain) protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
Neut_0452 | pyrC | Neut_0452 | Neut_1659 | TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: neu:NE1664 dihydroorotase. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.914 |
Neut_0452 | pyrD | Neut_0452 | Neut_0646 | TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: neu:NE1664 dihydroorotase. | Dihydroorotate oxidase A; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.996 |
Neut_0452 | pyrE | Neut_0452 | Neut_2050 | TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: neu:NE1664 dihydroorotase. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.961 |
carA | Neut_0452 | Neut_0454 | Neut_0452 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain; KEGG: neu:NE1662 carbamoyl-phosphate synthase (small chain) protein; Belongs to the CarA family. | TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: neu:NE1664 dihydroorotase. | 0.997 |
carA | carB | Neut_0454 | Neut_0455 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain; KEGG: neu:NE1662 carbamoyl-phosphate synthase (small chain) protein; Belongs to the CarA family. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: neu:NE1661 carbamoyl-phosphate synthase:methylglyoxal synthase-like domain; Belongs to the CarB family. | 0.999 |
carA | guaA | Neut_0454 | Neut_2251 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain; KEGG: neu:NE1662 carbamoyl-phosphate synthase (small chain) protein; Belongs to the CarA family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.582 |
carA | purL | Neut_0454 | Neut_0140 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain; KEGG: neu:NE1662 carbamoyl-phosphate synthase (small chain) protein; Belongs to the CarA family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.980 |
carA | pyrB | Neut_0454 | Neut_0451 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain; KEGG: neu:NE1662 carbamoyl-phosphate synthase (small chain) protein; Belongs to the CarA family. | TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; KEGG: neu:NE1665 aspartate carbamoyltransferase (catalytic chain) protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carA | pyrC | Neut_0454 | Neut_1659 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain; KEGG: neu:NE1662 carbamoyl-phosphate synthase (small chain) protein; Belongs to the CarA family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.544 |
carA | pyrD | Neut_0454 | Neut_0646 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain; KEGG: neu:NE1662 carbamoyl-phosphate synthase (small chain) protein; Belongs to the CarA family. | Dihydroorotate oxidase A; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.965 |
carA | pyrE | Neut_0454 | Neut_2050 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain; KEGG: neu:NE1662 carbamoyl-phosphate synthase (small chain) protein; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.953 |
carB | Neut_0452 | Neut_0455 | Neut_0452 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: neu:NE1661 carbamoyl-phosphate synthase:methylglyoxal synthase-like domain; Belongs to the CarB family. | TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: neu:NE1664 dihydroorotase. | 0.997 |
carB | carA | Neut_0455 | Neut_0454 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: neu:NE1661 carbamoyl-phosphate synthase:methylglyoxal synthase-like domain; Belongs to the CarB family. | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain; KEGG: neu:NE1662 carbamoyl-phosphate synthase (small chain) protein; Belongs to the CarA family. | 0.999 |
carB | guaA | Neut_0455 | Neut_2251 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: neu:NE1661 carbamoyl-phosphate synthase:methylglyoxal synthase-like domain; Belongs to the CarB family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.781 |
carB | metG | Neut_0455 | Neut_1921 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: neu:NE1661 carbamoyl-phosphate synthase:methylglyoxal synthase-like domain; Belongs to the CarB family. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.436 |