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acsA protein (Nitrosomonas eutropha) - STRING interaction network
"acsA" - Acetyl-coenzyme A synthetase in Nitrosomonas eutropha
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family (655 aa)    
Predicted Functional Partners:
Neut_1995
Phosphate acetyltransferase; Involved in acetate metabolism; In the N-terminal section; belongs to the CobB/CobQ family (709 aa)
   
 
  0.970
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family (391 aa)
     
 
  0.964
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily (510 aa)
   
 
  0.956
Neut_2587
PFAM- aldehyde dehydrogenase; KEGG- bte-BTH_I0706 aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family (478 aa)
   
  0.942
Neut_0700
PFAM- aldehyde dehydrogenase; KEGG- neu-NE2000 aldehyde dehydrogenase family (452 aa)
   
  0.942
Neut_0610
KEGG- neu-NE2262 beta-ketothiolase; TIGRFAM- acetyl-CoA acetyltransferases; PFAM- Thiolase; Belongs to the thiolase family (392 aa)
   
 
  0.931
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA; Belongs to the AccD/PCCB family (296 aa)
       
  0.931
Neut_0606
Succinate--CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit (390 aa)
   
 
  0.931
Neut_1899
Acetyl-CoA carboxylase carboxyltransferase subunit alpha; TIGRFAM- acetyl-CoA carboxylase, biotin carboxylase; PFAM- Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG- neu-NE0653 biotin carboxylase protein (452 aa)
   
  0.930
Neut_0861
KEGG- neu-NE2373 citrate synthase; TIGRFAM- citrate synthase I; PFAM- Citrate synthase; Belongs to the citrate synthase family (427 aa)
   
 
  0.929
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha C91, Nitrosomonas eutropha, Nitrosomonas eutropha C91, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
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