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hisF protein (Nitrosomonas eutropha) - STRING interaction network
"hisF" - Imidazole glycerol phosphate synthase subunit HisF in Nitrosomonas eutropha
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Predicted Interactions
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textmining
co-expression
protein homology
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hisFImidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (258 aa)    
Predicted Functional Partners:
hisH
Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (212 aa)
  0.999
hisB
PFAM- imidazoleglycerol-phosphate dehydratase; KEGG- neu-NE0646 imidazoleglycerol-phosphate dehydratase (195 aa)
  0.999
hisI
Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP (129 aa)
   
  0.999
hisA
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; TIGRFAM- phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM- histidine biosynthesis; KEGG- neu-NE0644 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase (248 aa)
 
 
0.997
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (432 aa)
 
  0.996
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity; Belongs to the ATP phosphoribosyltransferase family. Short subfamily (216 aa)
 
 
  0.983
hisE
PFAM- phosphoribosyl-ATP pyrophosphohydrolase; KEGG- neu-NE0641 phosphoribosyl-ATP pyrophosphohydrolase (117 aa)
 
   
  0.981
Neut_1905
TIGRFAM- histidinol-phosphate aminotransferase; PFAM- aminotransferase, class I and II; KEGG- neu-NE0647 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily (359 aa)
 
  0.972
Neut_1569
TIGRFAM- histidinol-phosphate aminotransferase; PFAM- aminotransferase, class I and II; KEGG- neu-NE0336 putative aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily (372 aa)
 
  0.896
purH
Bifunctional purine biosynthesis protein PurH; KEGG- neu-NE0876 probable phosphoribosylaminoimidazolecarboxamide formyltransferase and IMP cyclodydrolase transmembrane protein; TIGRFAM- phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM- AICARFT/IMPCHase bienzyme; MGS domain protein (520 aa)
   
 
    0.872
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha C91, Nitrosomonas eutropha, Nitrosomonas eutropha C91, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
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