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gcvH protein (Nitrosomonas eutropha) - STRING interaction network
"gcvH" - Glycine cleavage system H protein in Nitrosomonas eutropha
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query proteins and first shell of interactors
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second shell of interactors
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (129 aa)    
Predicted Functional Partners:
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine (363 aa)
  0.999
gcvPB
Probable glycine dehydrogenase (decarboxylating) subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily (483 aa)
  0.998
gcvPA
Probable glycine dehydrogenase (decarboxylating) subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (451 aa)
  0.998
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (416 aa)
   
 
  0.970
Neut_0200
Alanine-glyoxylate aminotransferase apoenzyme; PFAM- aminotransferase, class V; KEGG- neu-NE0034 aminotransferase class-V (404 aa)
     
 
  0.909
Neut_1773
TIGRFAM- dihydrolipoamide dehydrogenase; PFAM- FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG- neu-NE2319 dihydrolipoamide dehydrogenase (486 aa)
 
 
  0.876
lipB
Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (225 aa)
   
 
  0.872
birA
Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor (329 aa)
         
  0.865
Neut_2103
TIGRFAM- dihydrolipoamide dehydrogenase; PFAM- biotin/lipoyl attachment domain-containing protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; KEGG- neu-NE2157 dihydrolipoamide dehydrogenase (589 aa)
 
 
  0.855
Neut_1632
Pyridine nucleotide-disulfide oxidoreductase dimerization region; PFAM- FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG- neu-NE0774 dihydrolipoamide dehydrogenase (472 aa)
 
 
  0.850
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha C91, Nitrosomonas eutropha, Nitrosomonas eutropha C91, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
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