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aroC protein (Nitrosomonas eutropha) - STRING interaction network
"aroC" - Chorismate synthase in Nitrosomonas eutropha
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Predicted Interactions
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textmining
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protein homology
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aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system (390 aa)    
Predicted Functional Partners:
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate (433 aa)
 
 
  0.981
Neut_0135
Anthranilate synthase, component II; TIGRFAM- glutamine amidotransferase of anthranilate synthase; PFAM- glutamine amidotransferase class-I; KEGG- neu-NE0014 panthranilate synthase component II (glutamine amido-transferase) protein (200 aa)
 
 
  0.972
Neut_1570
TIGRFAM- chorismate mutase; PFAM- prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG- neu-NE0335 prephenate dehydratase (PDT)-chorismate mutase-ACT domain (352 aa)
 
 
  0.971
trpE
Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (495 aa)
 
 
  0.971
aroE
Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) (277 aa)
 
 
  0.912
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family (215 aa)
 
   
  0.850
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family (369 aa)
 
   
  0.840
ubiC
Probable chorismate pyruvate-lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family (154 aa)
         
  0.817
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5’-phosphoribosyl)-anthranilate (PRA) (341 aa)
   
   
  0.742
Neut_1261
TIGRFAM- acetolactate synthase, small subunit; PFAM- amino acid-binding ACT domain protein; KEGG- neu-NE1324 acetolactate synthase small subunit (163 aa)
   
   
  0.738
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha C91, Nitrosomonas eutropha, Nitrosomonas eutropha C91, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
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