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Neut_2048 protein (Nitrosomonas eutropha) - STRING interaction network
"Neut_2048" - KEGG: neu:NE1733 ATP dependent protease, chaperonin in Nitrosomonas eutropha
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Neut_2048KEGG- neu-NE1733 ATP dependent protease, chaperonin; TIGRFAM- ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM- AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART- AAA ATPase; Belongs to the ClpA/ClpB family (756 aa)    
Predicted Functional Partners:
clpS
ATP-dependent Clp protease adapter protein ClpS; Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (103 aa)
 
  0.997
dnaK
Chaperone protein DnaK; Acts as a chaperone (647 aa)
 
 
  0.850
grpE
Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- dependent [...] (196 aa)
   
 
  0.834
clpP
ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins; Belongs to the peptidase S14 family (214 aa)
     
 
  0.801
Neut_2049
TRAP dicarboxylate transporter-DctP subunit; Part of the tripartite ATP-independent periplasmic (TRAP) transport system (353 aa)
              0.801
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (369 aa)
   
 
  0.798
Neut_1596
PFAM- heat shock protein Hsp20; KEGG- neu-NE2074 heat shock HSP20 (alpha crystallin) proteins family; Belongs to the small heat shock protein (HSP20) family (145 aa)
 
 
  0.786
htpG
Chaperone protein HtpG; Molecular chaperone. Has ATPase activity (640 aa)
   
 
  0.757
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (242 aa)
   
        0.734
groL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (547 aa)
   
 
  0.721
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha C91, Nitrosomonas eutropha, Nitrosomonas eutropha C91, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
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