node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Neut_0889 | fusA | Neut_0889 | Neut_0555 | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: neu:NE1807 putative ATP-dependent RNA helicase protein; Belongs to the DEAD box helicase family. | Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] | 0.947 |
Neut_0889 | pnp | Neut_0889 | Neut_2157 | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: neu:NE1807 putative ATP-dependent RNA helicase protein; Belongs to the DEAD box helicase family. | 3' exoribonuclease; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.933 |
Neut_0889 | rplD | Neut_0889 | Neut_0559 | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: neu:NE1807 putative ATP-dependent RNA helicase protein; Belongs to the DEAD box helicase family. | LSU ribosomal protein L4P; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.836 |
Neut_0889 | rpoA | Neut_0889 | Neut_0583 | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: neu:NE1807 putative ATP-dependent RNA helicase protein; Belongs to the DEAD box helicase family. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.759 |
Neut_0889 | rpoB | Neut_0889 | Neut_1795 | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: neu:NE1807 putative ATP-dependent RNA helicase protein; Belongs to the DEAD box helicase family. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.749 |
Neut_0889 | rpsD | Neut_0889 | Neut_0582 | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: neu:NE1807 putative ATP-dependent RNA helicase protein; Belongs to the DEAD box helicase family. | SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.830 |
Neut_1668 | fusA | Neut_1668 | Neut_0555 | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: neu:NE2040 ATP-dependent RNA helicase RhlE; Belongs to the DEAD box helicase family. | Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] | 0.947 |
Neut_1668 | pnp | Neut_1668 | Neut_2157 | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: neu:NE2040 ATP-dependent RNA helicase RhlE; Belongs to the DEAD box helicase family. | 3' exoribonuclease; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.933 |
Neut_1668 | rplD | Neut_1668 | Neut_0559 | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: neu:NE2040 ATP-dependent RNA helicase RhlE; Belongs to the DEAD box helicase family. | LSU ribosomal protein L4P; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.836 |
Neut_1668 | rpoA | Neut_1668 | Neut_0583 | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: neu:NE2040 ATP-dependent RNA helicase RhlE; Belongs to the DEAD box helicase family. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.759 |
Neut_1668 | rpoB | Neut_1668 | Neut_1795 | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: neu:NE2040 ATP-dependent RNA helicase RhlE; Belongs to the DEAD box helicase family. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.749 |
Neut_1668 | rpsD | Neut_1668 | Neut_0582 | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: neu:NE2040 ATP-dependent RNA helicase RhlE; Belongs to the DEAD box helicase family. | SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.830 |
fusA | Neut_0889 | Neut_0555 | Neut_0889 | Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: neu:NE1807 putative ATP-dependent RNA helicase protein; Belongs to the DEAD box helicase family. | 0.947 |
fusA | Neut_1668 | Neut_0555 | Neut_1668 | Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: neu:NE2040 ATP-dependent RNA helicase RhlE; Belongs to the DEAD box helicase family. | 0.947 |
fusA | infB | Neut_0555 | Neut_1646 | Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] | Bacterial translation initiation factor 2 (bIF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.942 |
fusA | nusA | Neut_0555 | Neut_1647 | Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] | NusA antitermination factor; Participates in both transcription termination and antitermination. | 0.940 |
fusA | pnp | Neut_0555 | Neut_2157 | Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] | 3' exoribonuclease; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.927 |
fusA | rho | Neut_0555 | Neut_2479 | Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.741 |
fusA | rplD | Neut_0555 | Neut_0559 | Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] | LSU ribosomal protein L4P; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.996 |
fusA | rpoA | Neut_0555 | Neut_0583 | Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.973 |