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pcnB protein (Nitrosomonas eutropha) - STRING interaction network
"pcnB" - Poly(A) polymerase I in Nitrosomonas eutropha
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
pcnBPoly(A) polymerase I; Adds poly(A) tail to the 3’ end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control (462 aa)    
Predicted Functional Partners:
Neut_2295
KEGG- neu-NE0070 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; TIGRFAM- 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM- 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK (170 aa)
   
   
  0.922
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate; Belongs to the PanB family (269 aa)
   
   
  0.897
Neut_2294
PFAM- deoxynucleoside kinase; KEGG- neu-NE0071 deoxynucleoside kinase (214 aa)
   
        0.890
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate; Belongs to the pantothenate synthetase family (277 aa)
   
   
  0.851
dksA
RNA polymerase-binding transcription factor DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters (141 aa)
            0.790
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (906 aa)
 
   
  0.756
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3’- to 5’-direction (705 aa)
     
 
  0.634
hfq
RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (80 aa)
       
 
  0.625
rnr
Ribonuclease R; 3’-5’ exoribonuclease that releases 5’-nucleoside monophosphates and is involved in maturation of structured RNAs (734 aa)
   
 
  0.585
Neut_1336
KEGG- neu-NE0833 HrpA-like helicases; TIGRFAM- ATP-dependent helicase HrpA; PFAM- helicase domain protein; helicase-associated domain protein; protein of unknown function DUF1605; SMART- AAA ATPase; DEAD/DEAH box helicase domain protein (1253 aa)
 
      0.555
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha C91, Nitrosomonas eutropha, Nitrosomonas eutropha C91, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
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