• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
hprK protein (Nitrosomonas eutropha) - STRING interaction network
"hprK" - HPr kinase/phosphorylase in Nitrosomonas eutropha
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hprKHPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) (323 aa)    
Predicted Functional Partners:
Neut_2305
PTS IIA-like nitrogen-regulatory protein PtsN; PFAM- phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; KEGG- neu-NE0060 phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) (156 aa)
 
     
  0.934
Neut_0530
TIGRFAM- phosphocarrier, HPr family; PFAM- phosphocarrier HPr protein; KEGG- neu-NE2184 phosphocarrier HPr protein (89 aa)
 
 
 
  0.838
Neut_0529
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (575 aa)
 
     
  0.733
Neut_2433
PFAM- ROK family protein; phosphoglucose isomerase (PGI); KEGG- dra-DR1742 glucose-6-phosphate isomerase; Belongs to the GPI family (768 aa)
         
  0.701
ubiX
Flavin prenyltransferase UbiX; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN (204 aa)
              0.635
Neut_2304
TIGRFAM- ribosomal subunit interface protein; PFAM- sigma 54 modulation protein/ribosomal protein S30EA; KEGG- neu-NE0061 sigma 54 modulation protein / S30EA ribosomal protein (111 aa)
              0.611
Neut_0868
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family (776 aa)
         
  0.575
fabZ
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (147 aa)
           
  0.538
lptA
Lipopolysaccharide export system protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane (183 aa)
 
          0.537
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (933 aa)
           
  0.532
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha C91, Nitrosomonas eutropha, Nitrosomonas eutropha C91, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
Server load: low (7%) [HD]