• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
ribH protein (Nitrosomonas eutropha) - STRING interaction network
"ribH" - 6,7-dimethyl-8-ribityllumazine synthase in Nitrosomonas eutropha
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (165 aa)    
Predicted Functional Partners:
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family (369 aa)
 
  0.999
Neut_1091
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family (367 aa)
 
 
  0.999
Neut_2515
TIGRFAM- riboflavin synthase, alpha subunit; PFAM- Lumazine-binding protein; KEGG- neu-NE2555 riboflavin synthase alpha chain family lumazine binding domain (201 aa)
 
  0.998
nusB
Transcription antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons (167 aa)
 
   
  0.992
Neut_1440
Riboflavin biosynthesis protein; KEGG- neu-NE1150 cytidylyltransferase-riboflavin kinase / FAD synthetase; TIGRFAM- riboflavin biosynthesis protein RibF; PFAM- Riboflavin kinase / FAD synthetase; cytidylyltransferase; Belongs to the ribF family (325 aa)
 
 
  0.962
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family (328 aa)
   
   
  0.634
Neut_0783
Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4’-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4’-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family (401 aa)
 
 
  0.622
Neut_2520
Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) (180 aa)
   
   
  0.604
Neut_2521
PFAM- CinA domain protein; KEGG- neu-NE2561 competence-damaged protein; Belongs to the CinA family (180 aa)
              0.599
pyrD
Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily (342 aa)
   
   
  0.597
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha C91, Nitrosomonas eutropha, Nitrosomonas eutropha C91, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
Server load: low (14%) [HD]