node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sfum_0526 | Sfum_2605 | Sfum_0526 | Sfum_2605 | PFAM: phage integrase family protein; KEGG: lip:LI0173 prophage DLP12 integrase. | Chromosome segregation ATPase; PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: tbd:Tbd_2806 chromosome partitioning protein ParA. | 0.408 |
Sfum_0526 | xerC | Sfum_0526 | Sfum_0067 | PFAM: phage integrase family protein; KEGG: lip:LI0173 prophage DLP12 integrase. | Phage integrase family protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.765 |
Sfum_1598 | Sfum_2605 | Sfum_1598 | Sfum_2605 | DNA translocase FtsK; PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: gme:Gmet_0367 cell divisionFtsK/SpoIIIE. | Chromosome segregation ATPase; PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: tbd:Tbd_2806 chromosome partitioning protein ParA. | 0.655 |
Sfum_1598 | Sfum_2606 | Sfum_1598 | Sfum_2606 | DNA translocase FtsK; PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: gme:Gmet_0367 cell divisionFtsK/SpoIIIE. | TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: pca:Pcar_3138 ParB-like domain protein; Belongs to the ParB family. | 0.793 |
Sfum_1598 | mfd | Sfum_1598 | Sfum_3479 | DNA translocase FtsK; PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: gme:Gmet_0367 cell divisionFtsK/SpoIIIE. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.675 |
Sfum_1598 | recR | Sfum_1598 | Sfum_2791 | DNA translocase FtsK; PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: gme:Gmet_0367 cell divisionFtsK/SpoIIIE. | DNA replication and repair protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.441 |
Sfum_1598 | topA | Sfum_1598 | Sfum_0213 | DNA translocase FtsK; PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: gme:Gmet_0367 cell divisionFtsK/SpoIIIE. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.612 |
Sfum_1598 | xerC | Sfum_1598 | Sfum_0067 | DNA translocase FtsK; PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: gme:Gmet_0367 cell divisionFtsK/SpoIIIE. | Phage integrase family protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.658 |
Sfum_2605 | Sfum_0526 | Sfum_2605 | Sfum_0526 | Chromosome segregation ATPase; PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: tbd:Tbd_2806 chromosome partitioning protein ParA. | PFAM: phage integrase family protein; KEGG: lip:LI0173 prophage DLP12 integrase. | 0.408 |
Sfum_2605 | Sfum_1598 | Sfum_2605 | Sfum_1598 | Chromosome segregation ATPase; PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: tbd:Tbd_2806 chromosome partitioning protein ParA. | DNA translocase FtsK; PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: gme:Gmet_0367 cell divisionFtsK/SpoIIIE. | 0.655 |
Sfum_2605 | Sfum_2606 | Sfum_2605 | Sfum_2606 | Chromosome segregation ATPase; PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: tbd:Tbd_2806 chromosome partitioning protein ParA. | TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: pca:Pcar_3138 ParB-like domain protein; Belongs to the ParB family. | 0.999 |
Sfum_2605 | topA | Sfum_2605 | Sfum_0213 | Chromosome segregation ATPase; PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: tbd:Tbd_2806 chromosome partitioning protein ParA. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.493 |
Sfum_2605 | xerC | Sfum_2605 | Sfum_0067 | Chromosome segregation ATPase; PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: tbd:Tbd_2806 chromosome partitioning protein ParA. | Phage integrase family protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.527 |
Sfum_2606 | Sfum_1598 | Sfum_2606 | Sfum_1598 | TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: pca:Pcar_3138 ParB-like domain protein; Belongs to the ParB family. | DNA translocase FtsK; PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: gme:Gmet_0367 cell divisionFtsK/SpoIIIE. | 0.793 |
Sfum_2606 | Sfum_2605 | Sfum_2606 | Sfum_2605 | TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: pca:Pcar_3138 ParB-like domain protein; Belongs to the ParB family. | Chromosome segregation ATPase; PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: tbd:Tbd_2806 chromosome partitioning protein ParA. | 0.999 |
Sfum_2606 | topA | Sfum_2606 | Sfum_0213 | TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: pca:Pcar_3138 ParB-like domain protein; Belongs to the ParB family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.447 |
Sfum_2606 | xerC | Sfum_2606 | Sfum_0067 | TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: pca:Pcar_3138 ParB-like domain protein; Belongs to the ParB family. | Phage integrase family protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.474 |
argB | hslU | Sfum_0064 | Sfum_0065 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.604 |
argB | hslV | Sfum_0064 | Sfum_0066 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | CodW component of CodWX peptidase. Threonine peptidase. MEROPS family T01B; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.602 |
argB | xerC | Sfum_0064 | Sfum_0067 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Phage integrase family protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.485 |