STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (362 aa)    
Predicted Functional Partners:
Sfum_1061
TRNA-uridine 2-sulfurtransferase; KEGG: sat:SYN_01419 putative tRNA (5-methylaminomethyl-2-thiouridylate) -methyltransferase / fibronectin/fibrinogen-binding protein.
     
  0.900
Sfum_0166
RNA modification enzyme, MiaB family; KEGG: sat:SYN_00797 tRNA 2-methylthioadenosine synthase -like protein; TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme; PFAM: Radical SAM domain protein; Protein of unknown function UPF0004-like; SMART: Elongator protein 3/MiaB/NifB.
  
  
 0.822
mnmG
Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
  
 0.734
mnmE
tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
 0.732
Sfum_1060
PFAM: PP-loop domain protein; KEGG: chy:CHY_1281 conserved hypothetical protein TIGR00268.
    
 0.672
Sfum_3182
Riboflavin kinase / FMN adenylyltransferase; TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain; PFAM: Riboflavin kinase / FAD synthetase; KEGG: gme:Gmet_1388 riboflavin kinase / FAD synthetase; Belongs to the ribF family.
 
    0.655
Sfum_2808
PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; Pyridoxal-dependent decarboxylase; KEGG: bma:BMAA0379 cysteine desulfurase.
 
  
 0.570
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
  
 0.554
Sfum_1378
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.553
Sfum_2683
Aminotransferase, class V; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
 
  
 0.549
Your Current Organism:
Syntrophobacter fumaroxidans
NCBI taxonomy Id: 335543
Other names: S. fumaroxidans MPOB, Syntrophobacter fumaroxidans DSM 10017, Syntrophobacter fumaroxidans MPOB, Syntrophobacter fumaroxidans str. MPOB, Syntrophobacter fumaroxidans strain MPOB, Syntrophobacter sp. DSM 10017, syntrophic propionate-oxidizing bacterium DSM 10017
Server load: low (22%) [HD]