node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sfum_0006 | Sfum_0376 | Sfum_0006 | Sfum_0376 | KpsF/GutQ family protein; KEGG: sat:SYN_00471 arabinose-5-phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | PFAM: lipid A biosynthesis acyltransferase; KEGG: aba:Acid345_2346 lipid A biosynthesis acyltransferase. | 0.781 |
Sfum_0006 | Sfum_2474 | Sfum_0006 | Sfum_2474 | KpsF/GutQ family protein; KEGG: sat:SYN_00471 arabinose-5-phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.869 |
Sfum_0006 | Sfum_3752 | Sfum_0006 | Sfum_3752 | KpsF/GutQ family protein; KEGG: sat:SYN_00471 arabinose-5-phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.869 |
Sfum_0006 | kdsA | Sfum_0006 | Sfum_2074 | KpsF/GutQ family protein; KEGG: sat:SYN_00471 arabinose-5-phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: pca:Pcar_1944 2-dehydro-3-deoxyphosphooctonate aldolase. | 0.989 |
Sfum_0006 | kdsB | Sfum_0006 | Sfum_0010 | KpsF/GutQ family protein; KEGG: sat:SYN_00471 arabinose-5-phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.880 |
Sfum_0006 | lpxA | Sfum_0006 | Sfum_3749 | KpsF/GutQ family protein; KEGG: sat:SYN_00471 arabinose-5-phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.867 |
Sfum_0006 | lpxB | Sfum_0006 | Sfum_3751 | KpsF/GutQ family protein; KEGG: sat:SYN_00471 arabinose-5-phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.868 |
Sfum_0006 | lpxC | Sfum_0006 | Sfum_1931 | KpsF/GutQ family protein; KEGG: sat:SYN_00471 arabinose-5-phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.869 |
Sfum_0006 | lpxD | Sfum_0006 | Sfum_3747 | KpsF/GutQ family protein; KEGG: sat:SYN_00471 arabinose-5-phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.872 |
Sfum_0006 | lpxK | Sfum_0006 | Sfum_0346 | KpsF/GutQ family protein; KEGG: sat:SYN_00471 arabinose-5-phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide synthase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.879 |
Sfum_0376 | Sfum_0006 | Sfum_0376 | Sfum_0006 | PFAM: lipid A biosynthesis acyltransferase; KEGG: aba:Acid345_2346 lipid A biosynthesis acyltransferase. | KpsF/GutQ family protein; KEGG: sat:SYN_00471 arabinose-5-phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | 0.781 |
Sfum_0376 | Sfum_2474 | Sfum_0376 | Sfum_2474 | PFAM: lipid A biosynthesis acyltransferase; KEGG: aba:Acid345_2346 lipid A biosynthesis acyltransferase. | Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.979 |
Sfum_0376 | Sfum_3752 | Sfum_0376 | Sfum_3752 | PFAM: lipid A biosynthesis acyltransferase; KEGG: aba:Acid345_2346 lipid A biosynthesis acyltransferase. | Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.978 |
Sfum_0376 | kdsA | Sfum_0376 | Sfum_2074 | PFAM: lipid A biosynthesis acyltransferase; KEGG: aba:Acid345_2346 lipid A biosynthesis acyltransferase. | TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: pca:Pcar_1944 2-dehydro-3-deoxyphosphooctonate aldolase. | 0.674 |
Sfum_0376 | kdsB | Sfum_0376 | Sfum_0010 | PFAM: lipid A biosynthesis acyltransferase; KEGG: aba:Acid345_2346 lipid A biosynthesis acyltransferase. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.727 |
Sfum_0376 | lpxA | Sfum_0376 | Sfum_3749 | PFAM: lipid A biosynthesis acyltransferase; KEGG: aba:Acid345_2346 lipid A biosynthesis acyltransferase. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.810 |
Sfum_0376 | lpxB | Sfum_0376 | Sfum_3751 | PFAM: lipid A biosynthesis acyltransferase; KEGG: aba:Acid345_2346 lipid A biosynthesis acyltransferase. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.806 |
Sfum_0376 | lpxC | Sfum_0376 | Sfum_1931 | PFAM: lipid A biosynthesis acyltransferase; KEGG: aba:Acid345_2346 lipid A biosynthesis acyltransferase. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.827 |
Sfum_0376 | lpxD | Sfum_0376 | Sfum_3747 | PFAM: lipid A biosynthesis acyltransferase; KEGG: aba:Acid345_2346 lipid A biosynthesis acyltransferase. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.819 |
Sfum_0376 | lpxK | Sfum_0376 | Sfum_0346 | PFAM: lipid A biosynthesis acyltransferase; KEGG: aba:Acid345_2346 lipid A biosynthesis acyltransferase. | lipid-A-disaccharide synthase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.835 |