node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sfum_0467 | birA | Sfum_0467 | Sfum_2610 | Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.451 |
Sfum_0467 | birA-2 | Sfum_0467 | Sfum_3720 | Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.451 |
Sfum_0467 | coaD | Sfum_0467 | Sfum_2992 | Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.936 |
Sfum_0467 | coaX | Sfum_0467 | Sfum_0549 | Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | 0.943 |
Sfum_0467 | panC | Sfum_0467 | Sfum_0369 | Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.887 |
Sfum_0546 | Sfum_0547 | Sfum_0546 | Sfum_0547 | UDP-N-acetylmuramate--L-alanine ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: dps:DP2930 probable UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diamino pimelate ligase. | PFAM: beta-lactamase; KEGG: dps:DP0647 hypothetical protein. | 0.849 |
Sfum_0546 | Sfum_0548 | Sfum_0546 | Sfum_0548 | UDP-N-acetylmuramate--L-alanine ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: dps:DP2930 probable UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diamino pimelate ligase. | PFAM: peptidase U61, LD-carboxypeptidase A; KEGG: sth:STH2808 putative muramoyltetrapeptide carboxypeptidase. | 0.863 |
Sfum_0546 | coaX | Sfum_0546 | Sfum_0549 | UDP-N-acetylmuramate--L-alanine ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: dps:DP2930 probable UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diamino pimelate ligase. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | 0.784 |
Sfum_0547 | Sfum_0546 | Sfum_0547 | Sfum_0546 | PFAM: beta-lactamase; KEGG: dps:DP0647 hypothetical protein. | UDP-N-acetylmuramate--L-alanine ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: dps:DP2930 probable UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diamino pimelate ligase. | 0.849 |
Sfum_0547 | Sfum_0548 | Sfum_0547 | Sfum_0548 | PFAM: beta-lactamase; KEGG: dps:DP0647 hypothetical protein. | PFAM: peptidase U61, LD-carboxypeptidase A; KEGG: sth:STH2808 putative muramoyltetrapeptide carboxypeptidase. | 0.927 |
Sfum_0547 | coaX | Sfum_0547 | Sfum_0549 | PFAM: beta-lactamase; KEGG: dps:DP0647 hypothetical protein. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | 0.789 |
Sfum_0548 | Sfum_0546 | Sfum_0548 | Sfum_0546 | PFAM: peptidase U61, LD-carboxypeptidase A; KEGG: sth:STH2808 putative muramoyltetrapeptide carboxypeptidase. | UDP-N-acetylmuramate--L-alanine ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: dps:DP2930 probable UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diamino pimelate ligase. | 0.863 |
Sfum_0548 | Sfum_0547 | Sfum_0548 | Sfum_0547 | PFAM: peptidase U61, LD-carboxypeptidase A; KEGG: sth:STH2808 putative muramoyltetrapeptide carboxypeptidase. | PFAM: beta-lactamase; KEGG: dps:DP0647 hypothetical protein. | 0.927 |
Sfum_0548 | coaX | Sfum_0548 | Sfum_0549 | PFAM: peptidase U61, LD-carboxypeptidase A; KEGG: sth:STH2808 putative muramoyltetrapeptide carboxypeptidase. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | 0.798 |
birA | Sfum_0467 | Sfum_2610 | Sfum_0467 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.451 |
birA | birA-2 | Sfum_2610 | Sfum_3720 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.929 |
birA | coaX | Sfum_2610 | Sfum_0549 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | 0.874 |
birA | panC | Sfum_2610 | Sfum_0369 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.521 |
birA | panD | Sfum_2610 | Sfum_0368 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | L-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.481 |
birA | tmk | Sfum_2610 | Sfum_0398 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.413 |