node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sfum_2719 | aroA | Sfum_2719 | Sfum_2720 | TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: peptidase S13, D-Ala-D-Ala carboxypeptidase C; KEGG: ade:Adeh_3807 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.519 |
Sfum_2719 | aroD | Sfum_2719 | Sfum_2722 | TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: peptidase S13, D-Ala-D-Ala carboxypeptidase C; KEGG: ade:Adeh_3807 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase. | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 0.444 |
Sfum_2719 | aroE | Sfum_2719 | Sfum_2721 | TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: peptidase S13, D-Ala-D-Ala carboxypeptidase C; KEGG: ade:Adeh_3807 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.526 |
Sfum_2723 | Sfum_2724 | Sfum_2723 | Sfum_2724 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | PFAM: 3-dehydroquinate synthase; KEGG: aae:aq_1922 3-dehydroquinate synthase. | 0.987 |
Sfum_2723 | Sfum_3724 | Sfum_2723 | Sfum_3724 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | Prephenate dehydratase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; DAHP synthetase I/KDSA; KEGG: tte:TTE1013 phospho-2-dehydro-3-deoxyheptonate aldolase. | 0.847 |
Sfum_2723 | aroA | Sfum_2723 | Sfum_2720 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.974 |
Sfum_2723 | aroB | Sfum_2723 | Sfum_2494 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.672 |
Sfum_2723 | aroC | Sfum_2723 | Sfum_0041 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.991 |
Sfum_2723 | aroD | Sfum_2723 | Sfum_2722 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 0.783 |
Sfum_2723 | aroE | Sfum_2723 | Sfum_2721 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.838 |
Sfum_2723 | aroK | Sfum_2723 | Sfum_1639 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.747 |
Sfum_2723 | birA | Sfum_2723 | Sfum_2610 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.433 |
Sfum_2724 | Sfum_2723 | Sfum_2724 | Sfum_2723 | PFAM: 3-dehydroquinate synthase; KEGG: aae:aq_1922 3-dehydroquinate synthase. | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | 0.987 |
Sfum_2724 | Sfum_3724 | Sfum_2724 | Sfum_3724 | PFAM: 3-dehydroquinate synthase; KEGG: aae:aq_1922 3-dehydroquinate synthase. | Prephenate dehydratase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; DAHP synthetase I/KDSA; KEGG: tte:TTE1013 phospho-2-dehydro-3-deoxyheptonate aldolase. | 0.725 |
Sfum_2724 | aroA | Sfum_2724 | Sfum_2720 | PFAM: 3-dehydroquinate synthase; KEGG: aae:aq_1922 3-dehydroquinate synthase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.641 |
Sfum_2724 | aroB | Sfum_2724 | Sfum_2494 | PFAM: 3-dehydroquinate synthase; KEGG: aae:aq_1922 3-dehydroquinate synthase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.900 |
Sfum_2724 | aroD | Sfum_2724 | Sfum_2722 | PFAM: 3-dehydroquinate synthase; KEGG: aae:aq_1922 3-dehydroquinate synthase. | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 0.935 |
Sfum_2724 | aroE | Sfum_2724 | Sfum_2721 | PFAM: 3-dehydroquinate synthase; KEGG: aae:aq_1922 3-dehydroquinate synthase. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.637 |
Sfum_3724 | Sfum_2723 | Sfum_3724 | Sfum_2723 | Prephenate dehydratase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; DAHP synthetase I/KDSA; KEGG: tte:TTE1013 phospho-2-dehydro-3-deoxyheptonate aldolase. | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | 0.847 |
Sfum_3724 | Sfum_2724 | Sfum_3724 | Sfum_2724 | Prephenate dehydratase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; DAHP synthetase I/KDSA; KEGG: tte:TTE1013 phospho-2-dehydro-3-deoxyheptonate aldolase. | PFAM: 3-dehydroquinate synthase; KEGG: aae:aq_1922 3-dehydroquinate synthase. | 0.725 |