node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sfum_0193 | panB | Sfum_0193 | Sfum_2737 | KEGG: cya:CYA_0945 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.654 |
Sfum_0193 | panC | Sfum_0193 | Sfum_0369 | KEGG: cya:CYA_0945 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.427 |
Sfum_1736 | Sfum_2753 | Sfum_1736 | Sfum_2753 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.924 |
Sfum_1736 | panB | Sfum_1736 | Sfum_2737 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.926 |
Sfum_1736 | panC | Sfum_1736 | Sfum_0369 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.926 |
Sfum_2753 | Sfum_1736 | Sfum_2753 | Sfum_1736 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.924 |
Sfum_2753 | panB | Sfum_2753 | Sfum_2737 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.993 |
Sfum_2753 | panC | Sfum_2753 | Sfum_0369 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.985 |
Sfum_3098 | Sfum_3708 | Sfum_3098 | Sfum_3708 | TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase, class IV; KEGG: dps:DP0192 probable branched-chain amino acid aminotransferase. | PFAM: aminotransferase, class IV; KEGG: rxy:Rxyl_0760 aminotransferase, class IV. | 0.900 |
Sfum_3098 | ilvD | Sfum_3098 | Sfum_0356 | TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase, class IV; KEGG: dps:DP0192 probable branched-chain amino acid aminotransferase. | KEGG: sat:SYN_01708 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.991 |
Sfum_3098 | panB | Sfum_3098 | Sfum_2737 | TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase, class IV; KEGG: dps:DP0192 probable branched-chain amino acid aminotransferase. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.925 |
Sfum_3708 | Sfum_3098 | Sfum_3708 | Sfum_3098 | PFAM: aminotransferase, class IV; KEGG: rxy:Rxyl_0760 aminotransferase, class IV. | TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase, class IV; KEGG: dps:DP0192 probable branched-chain amino acid aminotransferase. | 0.900 |
Sfum_3708 | ilvD | Sfum_3708 | Sfum_0356 | PFAM: aminotransferase, class IV; KEGG: rxy:Rxyl_0760 aminotransferase, class IV. | KEGG: sat:SYN_01708 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.986 |
Sfum_3708 | panB | Sfum_3708 | Sfum_2737 | PFAM: aminotransferase, class IV; KEGG: rxy:Rxyl_0760 aminotransferase, class IV. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.916 |
birA | birA-2 | Sfum_2610 | Sfum_3720 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.929 |
birA | panB | Sfum_2610 | Sfum_2737 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.583 |
birA | panC | Sfum_2610 | Sfum_0369 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.521 |
birA | panD | Sfum_2610 | Sfum_0368 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | L-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.481 |
birA-2 | birA | Sfum_3720 | Sfum_2610 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.929 |
birA-2 | panB | Sfum_3720 | Sfum_2737 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.583 |