STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folE2GTP cyclohydrolase; Converts GTP to 7,8-dihydroneopterin triphosphate. (257 aa)    
Predicted Functional Partners:
Sfum_0003
PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: mac:MA0956 6-pyruvoyltetrahydropterin synthase.
 
  
 0.937
Sfum_1986
PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: sat:SYN_01559 queuosine biosynthesis protein.
 
  
 0.935
ribBA
GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
 0.914
Sfum_0053
KEGG: sat:SYN_02163 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HppK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK.
    
 0.902
moaA
GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
    
  0.900
Sfum_1475
PFAM: pyruvate kinase; KEGG: sat:SYN_02952 pyruvate kinase; Belongs to the pyruvate kinase family.
    
  0.815
Sfum_2959
PFAM: pyruvate kinase; KEGG: sat:SYN_02952 pyruvate kinase; Belongs to the pyruvate kinase family.
    
  0.815
Sfum_0559
PFAM: Forkhead-associated protein; adenylyl cyclase class-3/4/guanylyl cyclase; GAF domain protein; KEGG: mxa:MXAN_3956 putative adenylate cyclase.
    
  0.806
Sfum_0500
PFAM: nucleoside diphosphate kinase; KEGG: tko:TK1307 nucleoside diphosphate kinase; Belongs to the NDK family.
    
  0.801
Sfum_0558
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein; KEGG: sat:SYN_01481 adenylate cyclase.
    
  0.801
Your Current Organism:
Syntrophobacter fumaroxidans
NCBI taxonomy Id: 335543
Other names: S. fumaroxidans MPOB, Syntrophobacter fumaroxidans DSM 10017, Syntrophobacter fumaroxidans MPOB, Syntrophobacter fumaroxidans str. MPOB, Syntrophobacter fumaroxidans strain MPOB, Syntrophobacter sp. DSM 10017, syntrophic propionate-oxidizing bacterium DSM 10017
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