STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UREG_02453Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (625 aa)    
Predicted Functional Partners:
UREG_03880
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 
0.996
UREG_01565
Methylenetetrahydrofolate dehydrogenase.
    
 0.974
UREG_00878
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.967
UREG_06833
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.967
UREG_05931
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
  
 
 0.963
UREG_07615
C-1-tetrahydrofolate synthase.
  
 
 0.960
UREG_01910
5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase.
  
 0.948
UREG_02640
Thymidylate synthase.
    
 0.933
UREG_03398
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
  
 
 0.786
UREG_03360
Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.
    
 0.759
Your Current Organism:
Uncinocarpus reesii
NCBI taxonomy Id: 336963
Other names: U. reesii 1704, Uncinocarpus reesii 1704
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.